AibGenesis™ Mouse Anti-Rhesus NLRP2 Antibody (CBMOAB-52755FYA)


Cat: CBMOAB-52755FYA

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  • Specifications
  • Application Information
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO52755FYA
SpecificityThis antibody binds to Rhesus NLRP2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. (From NCBI)
Product OverviewMouse Anti-Rhesus NLRP2 Antibody is a mouse antibody against NLRP2. It can be used for NLRP2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesNLR family pyrin domain containing 2; NLRP2
UniProt IDB0FPF0
Protein RefseqThe length of the protein is 1063 amino acids long.
The sequence is show below: MVSSTQVNFNLQALLEQLSQDELSKFKSLLRTVSLGNEVQKIPQKEVDEADGKQLAEILISHCHSYWTELATIQVFEKMHRVDLSERAKDELREAALKSFNKHKPLSLGITRKERQPVDVEEMLERFKAGTLECTETEEDVTVLTEVFKVKGEKSDNEDRYRLILKTKFREMWQSWPGDSKEVHVMAERYRMLIPFSNPRVLPGPFSHTVVLHSPAGLGKTTLANKLMLDWTEDDLIQKFKYAFYLSCRELSRLGPCSFAQMVFRDWPELQDDIPHILAQAHKILFVIDGFDELGAPPGALIQDICGDWEQQKPVPVLLGSLLKRKMLPKATLLVTTRPRALRDLRFLAEQPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPAPTCLTSTGLFLRFLCSQFPQGAQLRGALRALSLLAAQGLWAQMSVLHGEDLESAGVQESDLRLFLDRDILRQDGVAKGCYSFIHLSFQQFLTALFYALEKEEEEDRDGHAWDIGDVQKLLSREERLKNPDLIQAGRFLFGLANEKRVKELEATFGWRMSPEIKQELLRCDVSRKNGHFTAADLRELLCCLYESQEDELVKEVMAQFKEISLHLNAVDIAPSSFCFKHCQNLQKMSLQVIKKETLPENVAASESNAESERSQDDQHMLPFWTDLCSIFGSNKDLIVVEINNSFLSASLVRILCEQIASDTCRLWRVVFKNIFPADAYRNLCLALRGHKTVTHLTLQGPDQKDMLPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEANRSLMCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVSRELTHLCLAKNSLKDTGVKFLCEGLSYPECKLQALVLWNCDITSDGCCSLAKLLQEKSSLSCLDLGLNHIGVTGVKVLCEALSKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQSLITLDLGQNPLGSSGVKMLFKTLTRPGTLQTLRLKIDDFNDELHKLLEEIEENNPQLIIDTEKHDPWKKRPSSHDFMI.
For Research Use Only | Not For Clinical Use.
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