Mouse Anti-Rhesus SPN Antibody (CBMOAB-58950FYA)


Cat: CBMOAB-58950FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO58950FYA
SpecificityThis antibody binds to Rhesus SPN.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Extracellular region or secreted

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.
Product OverviewMouse Anti-Rhesus SPN Antibody is a mouse antibody against SPN. It can be used for SPN detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesSPN
UniProt IDF7FTV3
Protein RefseqThe length of the protein is 393 amino acids long.
The sequence is show below: MAVLLLLLGVLVVSPEALGDTTAVQTPTSGPLVSTSKYLSIDSEMYTASITSDPKADGTGDQTSALPPSTSVNEGSPLGTSLGASTGSPLSEPTTLQNVSFEMSSMPQENPHATSHPAVPITANSLGSHTMTGGTMTTNSPETSSRSGAPVTVAASSXXXXXXIAAGSLETSTGTTGPPVTMTTGSLEPSNVNTGPSVTMTTGSLEPSSGASGPQVSSVKLSTMMTPTTSTNASTVPFRNPDENSGGMLPVAVLVALLVVIVLVALLLLWRRRQKRRTGALVLSRGGKRNGVVDAWAGPAQVPEEGAVTVTVGGSGGDKGSGVPDGEGSGRRPTLTTFFGRRKSRQGSLAMEELKSGSGSNLKGEEEPLVASEDGALDAPAPDEPETGDRAAP.
For Research Use Only | Not For Clinical Use.
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