AibGenesis™ Mouse Anti-RPT2A Antibody (CBMOAB-40768FYC)


Cat: CBMOAB-40768FYC

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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-40768FYC Monoclonal A. thaliana (Arabidopsis thaliana), Arabidopsis (Arabidopsis lyrata) WB, ELISA MO40768FC 100 µg
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MO-AB-00892H Monoclonal Arabidopsis (Arabidopsis lyrata) WB, ELISA MO00892C 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana), Arabidopsis (Arabidopsis lyrata)
CloneMO40768FC
SpecificityThis antibody binds to Arabidopsis RPT2A.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Plasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (PubMed:22158466) (Probable). Interacts with transit peptides of proteins targeted to the chloroplast, and may be involved in the degradation of unimported plastid protein precursors (PubMed:24846764). Is required for the maintenance of postembryonic root and shoot meristems (PubMed:15073153, PubMed:21784786). Has a specific role in the regulation of organs size (PubMed:19500299, PubMed:19321709). Acts redundantly with RPT2B in the regulation of gametogenesis (PubMed:21784786, PubMed:22158466). With RPT2B plays a critical role in 26S proteasome assembly (PubMed:22158466). Acts as an upstream signaling component for inducing both defense and morphological phenotypes in the constitutive active uni-1D mutant (PubMed:21791544). Acts as negative regulator of endoreduplication in trichome cells (PubMed:20195883). May function after the completion of the third endoreduplication step (8C to 16C) mediated by RHL1 (PubMed:20195883). Acts as negative regulator of transcriptional gene silencing (TGS) at specific endogenous genes through DNA methylation (PubMed:22615900). Promotes post-transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS (PubMed:22615900). Involved in tolerance to zinc deficiency, possibly through alleviation of oxidative stresses or processing of poly-ubiquitinated proteins (PubMed:21389614). Required for resistance to the fungal pathogen Golovinomyces cichoracearum (PubMed:22577987). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Arabidopsis RPT2A Antibody is a mouse antibody against RPT2A. It can be used for RPT2A detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names26S proteasome regulatory subunit 4 homolog A; 26S proteasome AAA-ATPase subunit RPT2a; 26S proteasome subunit 4 homolog A; Protein HALTED ROOT; Regulatory particle triple-A ATPase subunit 2a; RPT2A; HLR; At4g29040
UniProt IDQ9SZD4
Protein RefseqThe length of the protein is 443 amino acids long. The sequence is show below: MGQGPSGGLNRQGDRKPDGGDKKEKKFEPAAPPARVGRKQRKQKGPEAAARLPTVTPSTKCKLRLLKLERIKDYLLMEEEFVANQERLKPQEEKAEEDRSKVDDLRGTPMSVGNLEELIDENHAIVSSSVGPEYYVGILSFVDKDQLEPGCSILMHNKVLSVVGILQDEVDPMVSVMKVEKAPLESYADIGGLEAQIQEIKEAVELPLTHPELYEDIGIKPPKGVILYGEPGTGKTLLAKAVANSTSATFLRVVGSELIQKYLGDGPKLVRELFRVADDLSPSIVFIDEIDAVGTKRYDAHSGGEREIQRTMLELLNQLDGFDSRGDVKVILATNRIESLDPALLRPGRIDRKIEFPLPDIKTRRRIFQIHTSKMTLSEDVNLEEFVMTKDEFSGADIKAICTEAGLLALRERRMKVTHPDFKKAKEKVMFKKKEGVPEGLYM.
For Research Use Only | Not For Clinical Use.
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