Rabbit Anti-SARS-CoV-2(2019-nCoV) Nucleocapsid Antibody (AA 1-419)

Cat: MO-NAB-00890W
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Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivitySARS-CoV-2 (2019-nCoV)
SpecificityRecognize SARS-CoV-2 nucleocapsid protein
ImmunogenRecombinant SARS-CoV-2 nucleocapsid protein (Met1-Ala419)
EpitopeAA 1-419
FormatLiquid or Lyophilized
BufferPBS, pH7.4, 50% glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

Application NotesElisa: 1:4000-1:8000


IntroductionCoronavirus is an enveloped virus with a positive-strand RNA genome and a spirally symmetrical nucleocapsid. In virus-infected primary cells and cells transfected with a plasmid expressing N protein, the coronavirus nucleoprotein is located in the cytoplasm and nucleolus, which is a subnuclear structure. Coronavirus N protein is necessary for the synthesis of coronavirus RNA and has RNA chaperone activity that may participate in template conversion. Nucleocapsid protein is the most abundant protein in coronavirus. During the assembly of the virion, the N protein binds to the viral RNA and leads to the formation of a spiral nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein, which is also involved in viral genome replication and regulation of cell signaling pathways.
Product OverviewProduced in rabbits immunized with purified, Recombinant SARS-CoV-2 Nucleocapsid protein
Alternative NamesNucleoprotein; N; NC; Protein N
UniProt IDP0DTC9
For Research Use Only | Not For Clinical Use.
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