Cat: MO-NAB-00878W
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | SARS-CoV-2 (2019-nCoV) |
| Clone | NW0801 |
| Specificity | Identify SARS-CoV-2 spike glycoprotein |
| Immunogen | Recombinant SARS-CoV-2 (2019-nCoV) spike protein fragment 1[679-833] |
| Epitope | AA 679-833 |
| Format | Liquid |
| Buffer | PBS, pH7.4, 50% glycerol |
| Storage | Store at 2 to 8°C for one week. From the date of receipt, store at -20 to -80 °C for 12 months. Avoid repeated freeze-thaw cycles. |
Application Information
| Application | WB |
| Application Notes | WB: 1:1000-4000 |
Target
| Introduction | Coronavirus disease 2019 is a newly emerging infectious disease that is currently spreading globally. It is caused by a new type of coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2 plays a key role in the process of receptor recognition and cell membrane fusion, and is composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain that recognizes and binds to the host receptor angiotensin converting enzyme 2, while the S2 subunit mediates viral cell membrane fusion by forming a six-helix bundle through two heptapeptide repeat domains. In this review, we focused on the latest research progress in the structure, function and development of antiviral drugs targeting S protein. |
| Product Overview | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant SARS-CoV-2(2019-nCoV) Spike glycoprotein. |
| Alternative Names | Spike glycoprotein; S glycoprotei; E2; Peplomer protein; Spike protein S1; Spike protein S2; Spike protein S2; S |
| UniProt ID | P0DTC2 |
For Research Use Only | Not For Clinical Use.