Mouse Anti-SARS-CoV-2(2019-nCoV) Spike glycoprotein S1 Antibody (AA 679-833)


Cat: MO-NAB-00878W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivitySARS-CoV-2 (2019-nCoV)
CloneNW0801
SpecificityIdentify SARS-CoV-2 spike glycoprotein
ImmunogenRecombinant SARS-CoV-2 (2019-nCoV) spike protein fragment 1[679-833]
EpitopeAA 679-833
FormatLiquid or Lyophilized
BufferPBS, pH7.4, 50% glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationWB
Application NotesWB: 1:1000-4000

Target

IntroductionCoronavirus disease 2019 is a newly emerging infectious disease that is currently spreading globally. It is caused by a new type of coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2 plays a key role in the process of receptor recognition and cell membrane fusion, and is composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain that recognizes and binds to the host receptor angiotensin converting enzyme 2, while the S2 subunit mediates viral cell membrane fusion by forming a six-helix bundle through two heptapeptide repeat domains. In this review, we focused on the latest research progress in the structure, function and development of antiviral drugs targeting S protein.
Product OverviewThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant SARS-CoV-2(2019-nCoV) Spike glycoprotein.
Alternative NamesSpike glycoprotein; S glycoprotei; E2; Peplomer protein; Spike protein S1; Spike protein S2; Spike protein S2; S
UniProt IDP0DTC2
For Research Use Only | Not For Clinical Use.
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