Mouse Anti-Sheep AMH Antibody (MO-AB-14176Y)
Cat: MO-AB-14176Y
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Sheep (Ovis aries) |
| Clone | MO14176Y |
| Specificity | This antibody binds to Sheep AMH. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Extracellular region or secreted |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. |
| Product Overview | This product is a mouse antibody against AMH. It can be used for AMH detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Anti-Mullerian hormone; AMH |
| UniProt ID | T1SHH2 |
| Protein Refseq | The length of the protein is 575 amino acids long. The sequence is show below: MPGPSLSLALVLSAMGALLRPGTPREEVSNTSASPREQATGSGTLIFQQGWDWPLPSLWLPGSPQDPLCLVTLHGSGNGSRAPLRVVGSLSGYEQAFLEAVRRTHWGLSDLTTFAVCPAGDGQPVLPHLQRLQAWLGEPGGRWLVVLHLEEVTWEPTPLLRFQEPPPGGASPPELALLVLYPGPGLEVTVTGAGLPGTQSLCLTADSDFLALVVDPPEGAWRRPGLALTLQRRGNGEPLSTAQLQALLFGADSRCFTRKTPALLLLLSARSSAPMPAHGRLDLVPFPQPRPSPEPEEAPPSADPFLETLTRLVRALRGPPARSSPPRLALDPGALAGFPQGQVNLSDPTALERLLDGEEPLLLLLPPTAATTGVPATPQGPKSPLWAAGLARRVAAELQAAAAELRALPGLPPAAPPLLARLLALCPGNPDGPGGPLRALLLLKALQGLRAEWRGRERSGSARAQRSTGAAAADGPCALRELSVDLRAERSVLIPETYQANNCQGACGWPQSDRNPRYGNHVVLLLKMQARGAALARPPCCVPTAYTGKLLISLSEERISAHHVPNMVATECGCR. |
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For Research Use Only | Not For Clinical Use.
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