Mouse Anti-Sheep WNT6 Antibody (MO-AB-18265Y)


Cat: MO-AB-18265Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivitySheep (Ovis aries)
CloneMO18265Y
SpecificityThis antibody binds to Sheep WNT6.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationExtracellular region or secreted; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
Product OverviewThis product is a mouse antibody against WNT6. It can be used for WNT6 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein Wnt; WNT6
UniProt IDW5QEP7
Protein RefseqThe length of the protein is 312 amino acids long. The sequence is show below: SLPPTPSGGGLLLLLLLCPAHVGGLWWAVGSPLVMDPTSICRKARRLAGRQAELWTRPRSRLPAPRHAASRPPQRPRTQPGSCCLTAPPHLRDIRETAFVFAITAGGAPPPGAHAATSQSFLSELFLFFCAWFPLPSSKLLWAKAQWGWGGCGDDVDFGDEKSRLFMDAQHKRGRGDIRMLVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGKALLPAVRTLKPPGRADLLWAPRLCGGGGHRQESVLLEENCLCRFHWCCVVQCHRCRVRKELSLCL.
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For Research Use Only | Not For Clinical Use.
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