Mouse Anti-TBP Antibody, IgG2b kappa (MOFY-0922-FY58)


Cat: MOFY-0922-FY58
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Lot Number

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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MOFY-0922-FY58 Monoclonal S. cerevisiae, Chicken (Gallus gallus), Dog (Canis lupus familiaris), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Human (Homo sapiens), S. cerevisiae (Saccharomyces cerevisiae), Malaria parasite, Medaka (Oryzias latipes), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, IP, IF, ELISA MA-9 100 µg
CBMOAB-32631FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO32631FYA 100 µg
CBMOAB-59850FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO59850FYA 100 µg
CBMOAB-08791FYB Monoclonal Zebrafish (Danio rerio) WB, ELISA MO08791FYB 100 µg
MO-NAB-00052W Monoclonal Human (Homo sapiens), S. cerevisiae (Saccharomyces cerevisiae), Fruit fly (Drosophila melanogaster) WB 58C9 100 µg
MO-AB-33656W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO33656W 100 µg
MO-AB-01734R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO01734R 100 µg
MO-AB-30593R Monoclonal Pig (Sus scrofa) WB, ELISA MO30593R 100 µg
MO-AB-08291H Monoclonal Frog (Xenopus laevis) WB, ELISA MO08291C 100 µg
MO-AB-17321H Monoclonal Malaria parasite WB, ELISA MO17321C 100 µg
MO-AB-04301Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO04301Y 100 µg
MO-AB-17870Y Monoclonal Sheep (Ovis aries) WB, ELISA MO17870Y 100 µg
MOFY-0922-FY59 Monoclonal S. cerevisiae WB, IP, IF, ELISA MA-6 100 µg

Specifications

Host speciesMouse
Species ReactivityS. cerevisiae, Chicken (Gallus gallus), Dog (Canis lupus familiaris), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Human (Homo sapiens), S. cerevisiae (Saccharomyces cerevisiae), Malaria parasite, Medaka (Oryzias latipes), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMA-9
ImmunogenGenerated against amino acids 1-240 representing full-length TBP of S. cerevisiae
FormatLiquid or Lyophilized
BufferRefer to COA
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 95% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, IP, IF, ELISA

Target

IntroductionInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 25-42, and expansion of the number of repeats to 45-66 increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016]
Product OverviewMOFY-0922-FY58 is a mouse antibody against TBP. It can be used for TBP detection in Western Blot, Immunoprecipitation, Immunofluorescence, ELISA.
Alternative NamesTATA-Box Binding Protein; Transcription Initiation Factor TFIID TBP Subunit; TATA Sequence-Binding Protein; TATA-Box Factor; GTF2D1; TFIID; TATA-Box Binding Protein N-Terminal Domain
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For Research Use Only | Not For Clinical Use.
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