AibGenesis™ Mouse Anti-TFB1 Antibody (CBMOAB-04436CR)


Cat: CBMOAB-04436CR

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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-04436CR Monoclonal Yeast, Fruit fly (Drosophila melanogaster) WB, ELISA MO04436CR 100 µg
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CBMOAB-32927FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO32927FYA 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast, Fruit fly (Drosophila melanogaster)
CloneMO04436CR
SpecificityThis antibody binds to Yeast TFB1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription. (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Yeast TFB1 Antibody is a mouse antibody against TFB1. It can be used for TFB1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesRNA polymerase II transcription factor B subunit 1; General transcription and DNA repair factor IIH subunit TFB1; TFIIH subunit TFB1; RNA polymerase II transcription factor B 73 kDa subunit; RNA polymerase II transcription factor B p73 subunit; TFB1; YDR311W
UniProt IDP32776
Protein RefseqThe length of the protein is 642 amino acids long. The sequence is show below: MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEKRRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKLQQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFALSTSQKVGPYNVLSTIKPVASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEKIMQNDRGDVIIDRYLTLDQEFDRKDDDMLLHPVKKIIDLDGNIQDDPVVRGNRPDFTMQPGVDINGNSDGTVDILKGMNRLSEKMIMALKNEYSRTNLQNKSNITNDEEDEDNDERNELKIDDLNESYKTNYAIIHLKRNAHEKTTDNDAKSSADSIKNADLKVSNQQMLQQLSLVMDNLINKLDLNQVVPNNEVSNKINKRVITAIKINAKQAKHNNVNSALGSFVDNTSQANELEVKSTLPIDLLESCRMLHTTCCEFLKHFYIHFQSGEQKQASTVKKLYNHLKDCIEKLNELFQDVLNGDGESMSNTCTAYLKPVLNSITLATHKYDEYFNEYNNNSN.
For Research Use Only | Not For Clinical Use.
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