Mouse Anti-th Antibody (MOFY-1222-FY255)
Cat: MOFY-1222-FY255
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- Product Details
Specifications
| Host species | Mouse |
| Species Reactivity | Chicken, Frog, Human, Lizard, Monkey, Mouse, Rat, Vole, Zebrafish |
| Format | Liquid or Lyophilized |
| Buffer | Tris, pH 7.4, 50mM Sodium Chloride |
| Regulatory Status | For Research Use Only. Not For Clinical Use. |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | IHC, IP, WB |
Target
| Introduction | TH is the rate-limiting enzyme in the synthesis of the catecholamine neurotransmitters dopamine, epinephrine and norepinephrine and is responsible for the conversion of L-tyrosine to L-dopa. The synthesis of catecholamines is regulated by the interaction of TH with its cofactor tetrahydrobiopterin (BH4) and the substrates L-tyrosine and molecular oxygen. In humans, four TH mRNA splice variants (hTH1-hTH4) have been isolated, whereas subprimate species rely on a single form of TH. The hTH1-hTH4 variants are known to have identical catalytic domains but different N-terminal regulatory domains. Importantly, LNC1 reacts with the catalytic domain of TH and thus with all four isoforms of human TH. The role of TH in the synthesis of catecholamine neurotransmitters suggests a link between this enzyme and many neuropathic diseases characterized by irregular levels of catecholamines, such as Parkinson's disease, schizophrenia, and dystonia, as well as various cardiovascular disease. |
| Alternative Names | TH, TYH, EC 1.14.16.2 |
See other products for " TH "
| MO-AB-04669Y | Mouse Anti-Chicken TH Antibody (MO-AB-04669Y) |
| MO-AB-10201Y | Mouse Anti-Rabbit TH Antibody (MO-AB-10201Y) |
| MO-AB-21513R | Mouse Anti-Cattle TH Antibody (MO-AB-21513R) |
| MO-AB-70477W | Mouse Anti-Silkworm TH Antibody (MO-AB-70477W) |
| MO-AB-08404H | Mouse Anti-Frog th Antibody (MO-AB-08404H) |
| MO-AB-01751R | Mouse Anti-Medaka th Antibody (MO-AB-01751R) |
| MOFAB-796W | Mouse Anti-TH Antibody (MOFAB-796W) |
| MOFY-1222-FY63 | Rabbit Anti-th Antibody (MOFY-1222-FY63) |
| MO-AB-33709W | Mouse Anti-Dog TH Antibody (MO-AB-33709W) |
| MO-AB-42693W | Mouse Anti-Guinea pig TH Antibody (MO-AB-42693W) |
For Research Use Only | Not For Clinical Use.
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