Mouse Anti-TIMP-1 Antibody (MOFY-0522-FY162)


Cat: MOFY-0522-FY162
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Specifications

Host speciesMouse
Species ReactivityHuman, Macaque
FormatLiquid or Lyophilized
BufferPBS
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationELISA, IHC, WB
Application NotesWestern Blot: 1-2 µg/ml
Immunohistochemistry: 1-5 µg/ml
The optimal dilution should be determined by the end user.

Target

IntroductionThis gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
Alternative NamesProtein K07C11.3; timp-1
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CBMOAB-59205FYCMouse Anti-C. elegans timp-1 Antibody (CBMOAB-59205FYC)
For Research Use Only | Not For Clinical Use.
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