Mouse Anti-TJP1 Antibody (MO-AB-66226W)


Cat: MO-AB-66226W
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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-66226W Monoclonal Marmoset, Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Rhesus (Macaca mulatta) WB, ELISA MO66226W 100 µg
CBMOAB-60278FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO60278FYA 100 µg
MO-AB-23244W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO23244W 100 µg
MO-AB-33733W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO33733W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset, Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Rhesus (Macaca mulatta)
CloneMO66226W
SpecificityThis antibody binds to Marmoset TJP1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product OverviewMouse Anti-Marmoset TJP1 Antibody is a mouse antibody against TJP1. It can be used for TJP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesTight junction protein ZO-1 isoform a; TJP1
UniProt IDU3DJL3
Protein RefseqThe length of the protein is 1755 amino acids long.
The sequence is show below: MSARAAAAKSTAMEETAIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAEGQLQENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKKKVQIPVSRPDPEAVSDHEEDSYDDEVHDPRSSRSGVVTRRSEKMWPRERSASRERSLSPRSDRRSVASSQPAKPTKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDERATLLNVPDLSDSIHSANASERDDISEIQSLASDHSGRSHDRPPRRSRSRSPEQRSEPSDHSRHSPQQASNGSHRSRDEERISKPGAVSTPVKHADDHTPKTVEEFTVERNEKQTPSLPEPKPVYAQVGQPDVDLPVSPSDGVLPNSTHEDGILRPSMKLVKFRKGDSVGLRLAGGNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDVGDSFYIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDIYQIAKSEPRDAGTDQRSSGIIRLHTIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWVSEGKADGATSDDLDLHDDRLSYLSAPGSEYSMYSTDSRHTSDYEDTDTEGGAYTDQELDETLNDEVGTPPESAITRSSEPVREDSSGMHHENQTYPPYSPQAQPQPIHRIDSPGFKPASQQKAEASSPVPYLSPETNPASSTSAVNHNVNLTNVRLEEPTPAPSTSYSPQADSLRTPSTEAAHIMLRDQEPSLSSHVDPTKAYRKDPYPEEMMRQNHVFKQPAVGHSGHRPDKEPNVTYEPQLPYVEKQASRDLEQPTYRYESSTYTDQFSRNYDHRLRYEDRVPMYEEQWSYYDDKQPYPSRPPFENQHSRDLDSRQHPEESSERGYFPRFEEPAPLSYDSRPRYEQAPRASTLRHEEQPAAGYDTHGRHRPEAQPYPLVGPKPTEPKQYFEQYSRSYDQVPPQGFASRAGHFEPLHGAAAVPPLIPSSQHKPEGLPSNTKPLPPPPTLSEEEEDPAMKPQSVLTRVKMFENKRSASLETKKDVNDTAGFKPPEVASKPQGAPIIGPKPTSQNQFSEHDKTLYRIPEPQKPQVKPPEDIVRSNHYDPEEDEEYYRKQLSYFDRRSFENKPPAHVAASHLSEPAKPAHSQNQSNFSSYSSKGKPTEADVVDRSFGEKRYEPIQATPPPPPLPSQYTQPPQPVTSASLHIHSKGAHGEGNPVSLDFQNSLVSKPDPPPSQSKPATFRPPNREDTAQPAFYPQKSFPDKAPVNGAEQTQKTVTPAYNRFTPKPYTSSARPFERKFESPKFNHNLLPSETAHKPDLSSKSPTSPKTLVKSHSLVQPPEFDSGVETFSIHAEKPKYQINNISTVPKAIPVSPSAVEEDEDEDGHTVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLDKEKGETLLSPLVMCGPHGLKFLKPVELRLPHCASMTPDGDPKTWQNKCLPGDPNYLVGANCVSVLIDHF.
For Research Use Only | Not For Clinical Use.
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