Mouse Anti-TLR4 Antibody (MOFY-0722-FY58)


Cat: MOFY-0722-FY58
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Specifications

Host speciesMouse
Species ReactivityGoat
ImmunogenRecombinant Toll Like Receptor 4 (TLR4)
FormatLiquid or Lyophilized
Buffer0.01M PBS, pH7.4, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A or G

Application Information

ApplicationWB, IHC, ICC, IP
Application NotesWB: 0.5-2 µg/mL
IHC: 5-20 µg/mL
ICC: 5-20 µg/mL
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Alternative NamesToll Like Receptor 4; Toll-Like Receptor 4; HToll; Homolog Of Drosophila Toll; CD284 Antigen; ARMD10; CD284; TLR-4; TOLL;
For Research Use Only | Not For Clinical Use.
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