Guinea pig Anti-VEGFA Antibody (MOFY-0622-FY186)
Cat: MOFY-0622-FY186
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- Product Details
Specifications
| Host species | Guinea pig |
| Species Reactivity | Rabbit |
| Immunogen | Recombinant Vascular Endothelial Growth Factor A (VEGFA) |
| Format | Liquid or Lyophilized |
| Buffer | 0.01M PBS, pH7.4, 50% glycerol |
| Regulatory Status | For Research Use Only. Not For Clinical Use. |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | WB, IHC, ICC, IP |
| Application Notes | WB: 0.5-2 µg/mL IHC: 5-20 µg/mL ICC: 5-20 µg/mL The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2015] |
| Alternative Names | VEGF; VEGF-A; VPF; Vascular Endothelial Cell Growth Factor A; Vascular Permeability Factor |
See other products for " VEGFA "
| MOFY-0622-FY84 | Rabbit Anti-VEGFA Antibody (MOFY-0622-FY84) |
| MO-AB-04736Y | Mouse Anti-Chicken VEGFA Antibody (MO-AB-04736Y) |
| MO-AB-42838W | Mouse Anti-Guinea pig Vegfa Antibody (MO-AB-42838W) |
| MO-AB-47060W | Mouse Anti-Horse VEGFA Antibody (MO-AB-47060W) |
| MO-AB-38398W | Mouse Anti-Goat VEGFA Antibody (MO-AB-38398W) |
| MO-AB-18211Y | Mouse Anti-Sheep VEGFA Antibody (MO-AB-18211Y) |
| MO-AB-08790W | Mouse Anti-Cat VEGFA Antibody (MO-AB-08790W) |
| MOFY-0722-FY11 | Mouse Anti-VEGFA Antibody (MOFY-0722-FY11) |
| MOFY-0722-FY222 | Rabbit Anti-VEGFA Antibody (MOFY-0722-FY222) |
| MO-AB-22770R | Mouse Anti-Cattle VEGFA Antibody (MO-AB-22770R) |
For Research Use Only | Not For Clinical Use.
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