Mouse Anti-Yeast ADA2 Antibody (CBMOAB-00114CR)
Cat: CBMOAB-00114CR
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Yeast |
| Clone | MO00114CR |
| Specificity | This antibody binds to Yeast ADA2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8). SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation. SLIK is proposed to have partly overlapping functions with SAGA. It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus. ADA preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B. |
| Product Overview | Mouse Anti-Yeast ADA2 Antibody is a mouse antibody against ADA2. It can be used for ADA2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Transcriptional adapter 2; ADA2; YDR448W |
| UniProt ID | Q02336 |
| Protein Refseq | The length of the protein is 434 amino acids long. The sequence is show below: MSNKFHCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDYRIIETNSYPILCPDWGADEELQLIKGAQTLGLGNWQDIADHIGSRGKEEVKEHYLKYYLESKYYPIPDITQNIHVPQDEFLEQRRHRIESFRERPLEPPRKPMASVPSCHEVQGFMPGRLEFETEFENEAEGPVKDMVFEPDDQPLDIELKFAILDIYNSRLTTRAEKKRLLFENHLMDYRKLQAIDKKRSKEAKELYNRIKPFARVMTAQDFEEFSKDILEELHCRARIQQLQEWRSNGLTTLEAGLKYERDKQARISSFEKFGASTAASLSEGNSRYRSNSAHRSNAEYSQNYSENGGRKKNMTISDIQHAPDYALLSNDEQQLCIQLKILPKPYLVLKEVMFRELLKTGGNLSKSACRELLNIDPIKANRIYDFFQSQNWM. |
See other products for " ada2 "
| MO-AB-01223H | Mouse Anti-Frog ada2 Antibody (MO-AB-01223H) |
| CBMOAB-00371HCB | Mouse Anti-C. elegans ADA2 Antibody (CBMOAB-00371HCB) |
| MO-AB-00937W | Mouse Anti-Rhesus ADA2 Antibody (MO-AB-00937W) |
| MO-AB-47204W | Mouse Anti-Maize ada2 Antibody (MO-AB-47204W) |
| CBMOAB-18486FYB | Mouse Anti-Rice ADA2 Antibody (CBMOAB-18486FYB) |
For Research Use Only | Not For Clinical Use.
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