Mouse Anti-Yeast HTZ1 Antibody (CBMOAB-01779CR)


Cat: CBMOAB-01779CR
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast
CloneMO01779CR
SpecificityThis antibody binds to Yeast HTZ1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionVariant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received. Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins. Required for the RNA polymerase II and SPT15/TBP recruitment to the target genes. Involved in chromosome stability.
Product OverviewMouse Anti-Yeast HTZ1 Antibody is a mouse antibody against HTZ1. It can be used for HTZ1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesHistone H2A.Z; HTZ1; H2AZ HTA3; YOL012C
UniProt IDQ12692
Protein RefseqThe length of the protein is 134 amino acids long. The sequence is show below: MSGKAHGGKGKSGAKDSGSLRSQSSSARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLIRATIASGGVLPHINKALLLKVEKKGSKK.
For Research Use Only | Not For Clinical Use.
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