AibGenesis™ Mouse Anti-Zebrafish efna5b Antibody (CBMOAB-74557FYA)
Cat: CBMOAB-74557FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| Conjugate: | |
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- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Zebrafish (Danio rerio) |
| Clone | MO74557FYA |
| Specificity | This antibody binds to Zebrafish efna5b. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma Membrane |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the epha3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor epha2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation. Controls axon growth and may be involved in the creation of the retino-tectal map. (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Zebrafish efna5b Antibody is a mouse antibody against efna5b. It can be used for efna5b detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Ephrin-A5b; AL-1; EPH-related receptor tyrosine kinase ligand 7; LERK-7; ZfEPHL4; efna5b; al1 efna5 eplg7 lerk |
| UniProt ID | P79728 |
| Protein Refseq | The length of the protein is 228 amino acids long. The sequence is show below: MLQAEMIVFVGVILWMCVFSQEPSSKVMADRYAVFWNRTNPRFQRGDYHIDVCINDYLDVYCPHYEDSVPEERTERYVLYMVNYDGYSTCDHTAKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYYYISSMITETGRRSCLKLKVFVRPPNGCEKTIGVHDRVFVDDKVDNALEPRDDTSHEAEPSRSDVSTSGLRHQTSRPLLALLLLCISLYLLL. |
For Research Use Only | Not For Clinical Use.
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