Mouse Anti-Zebrafish grm4 Antibody (CBMOAB-63961FYA)
Cat: CBMOAB-63961FYA
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Zebrafish (Danio rerio) |
| Clone | MO63961FYA |
| Specificity | This antibody binds to Zebrafish grm4. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene. |
| Product Overview | Mouse Anti-Zebrafish grm4 Antibody is a mouse antibody against grm4. It can be used for grm4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Glutamate Metabotropic Receptor 4; grm4 |
| UniProt ID | E7F1E1 |
| Protein Refseq | The length of the protein is 916 amino acids long. The sequence is show below: MSSAMGKMIGWSNHHCQGSALVFLYLFMTALAARTKGPGHTHLNSIRIDGDISLGGLFPVHARGHEGKACGELKKEKGIHRLEAMLFALDRINNDHELLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTDVKCQGGGSPIITKPERVVGVIGASSSSVSIMVANILRLFKIPQVSYASTAPELSDNTRYDYFSRVVPPDTYQAQAMVDIVRDMRWNYVSTVASEGNYGESGVDAFIQKSREEGSVCISQSVKIPREPKPEEFDKIIKRLGENPNARVVIIFANEDDIRRLLQAAKKANQTGHFLWVGSDSWGSKISPVLNQEEMAEGAVTILPKRQSIRGFDRYFTSRTLENNRRNIWFAEFWENNFNCKLSRHALKKGSGIKKCTNQERIGKDSTYEQEGKVMFVIDAVYAMAHALHNMHKELCPGKVGLCSKMDPVDGAQLLKKIRDVKIAGIGGNPVQFNENGDAPGRYEIYQYQIKNKTAEYKIIGHWTDQLYLNVRAMQWPGGGRQVPTSICSQPCKPGWRKKIVKGMSCCWHCERCDGYQYQADLHTCKMCRFDLRPNKNHTGCQPIPIVKLEWSSPWAVIPVLIAILGIIATLFVVVTFIRYNDTPIVKASGRELSYVLLTGIFLCYATTFLMISTPDVGICSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKMTVSAPRFISPASQLIITFSLISVQLLGVCIWFAVDPSQALIDYEDQRTIDPEMARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTSQSTEKMYIQTTTLTISVSLSASVSLGMLYMPKVYVVLFHPEQNVAKRSTRSLKAVVTAATMSNKFNPKASLRPNGEAKSELCENLETQGLSPKQTYISYSNHAI. |
See other products for " GRM4 "
| MO-AB-56405W | Mouse Anti-Marmoset GRM4 Antibody (MO-AB-56405W) |
| MO-AB-21463W | Mouse Anti-Chimpanzee GRM4 Antibody (MO-AB-21463W) |
| MO-AB-26230R | Mouse Anti-Pig GRM4 Antibody (MO-AB-26230R) |
| CBMOAB-44152FYA | Mouse Anti-Rhesus GRM4 Antibody (CBMOAB-44152FYA) |
For Research Use Only | Not For Clinical Use.
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