AibGenesis™ Mouse Anti-Zebrafish smyd2b Antibody (CBMOAB-06608FYB)
Cat: CBMOAB-06608FYB
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Zebrafish (Danio rerio) |
| Clone | MO06608FYB |
| Specificity | This antibody binds to Zebrafish smyd2b. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 ''Lys-4'' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates ''Lys-370'' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at ''Lys-860''. (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Zebrafish smyd2b Antibody is a mouse antibody against smyd2b. It can be used for smyd2b detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | N-lysine methyltransferase SMYD2-B; smyd2 |
| UniProt ID | T1ECS2 |
| Protein Refseq | The length of the protein is 437 amino acids long. The sequence is show below: MMKAEGIPGIEQFASPGKGRGLRVSRAYGVGELLFSCPAYSYVLSVGERGLICEQCFTRKKGLAKCGKCKKAFYCNANCQKKNWPMHKLECQAMCAFGENWRPSETVRLVARIIARLKAQKERSPSEILLLLGEMEAHLEDMDNEKREMTEAHIAGLHQFYSKHLDFPDHQALLTLFSQVHCNGFTVEDEELSNLGLAIFPDIALLNHSCSPNVIVTYRGINAEVRAVKDISPGQEIYTSYIDLLYPTADRLERLRDMYYFSCDCKECTTKSMDVVKMSVRKRSDEIGEKEIKDMVRYARNSMENFRRAKQDKNILCGSFILEMCELSIDKMSTVFDDSNVYILHMMYQAMGICLFTEDYEGAVRYGEKVIKPFTVLYPAYSMNVASMFLKLGRLYIALDRKLAGIDAFQKALTIMEVVHGKDHTYVTELKQEMRDF. |
For Research Use Only | Not For Clinical Use.
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