Mouse Anti-ABCA4 Antibody (MOFAB-807W)


Cat: MOFAB-807W
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Specifications

Host speciesMouse
Species ReactivityBovine, Human, Mouse, Xenopus
CloneM3F4
FormatLiquid or Lyophilized
Buffer10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol.
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein G

Application Information

ApplicationIHC, WB
Application NotesOther applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]
Product OverviewThis product is a Mouse antibody against the ABCA4. It can be used for ABCA4 antibody detection in Immunohistochemistry, Western Blot.
Alternative NamesATP Binding Cassette Subfamily A Member 4; ATP-Binding Cassette, Sub-Family A (ABC1), Member 4; ATP-Binding Cassette Transporter, Retinal-Specific; ATP-Binding Cassette Sub-Family A Member 4; Stargardt Disease Protein; RIM ABC Transporter; RIM Protein; ABCR; RMP; Retinal-Specific ATP-Binding Cassette Transporter; ATP-Binding Transporter, Retina-Specific; ATP Binding Cassette Transporter;
UniProt IDP78363
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For Research Use Only | Not For Clinical Use.
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