Mouse Anti-alkB Antibody (CBMOAB-0078YC)

Cat: CBMOAB-0078YC

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-0078YC	Monoclonal	E. coli (Escherichia coli ), Fruit fly (Drosophila melanogaster)	WB, ELISA	MO0078YC		100 µg	Inquiry
Protein Refseq: The length of the protein is 216 amino acids long. The sequence is show below: MLDLFADAEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGKKE.
CBMOAB-00874FYA	Monoclonal	Fruit fly (Drosophila melanogaster)	WB, ELISA	MO00874FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 332 amino acids long. The sequence is show below: MFKLVFKQYKCKSTSPDLTEVVKIDDCVVKGNDQEKSDNNIVQRLSISNVESLQTMPGVKSPKDWRTYTLTNHPGIIVIRNPFSERGRRYWSARCLRDFPRTPNIVNLNERLFDESVRSDWWKQLNLCSDGVEFQRIKSAMRWTTFGYHHNWDTKIYDEEMQSPFPEDLSSLCGLFAQALGYADFKPEAAIVNYYPVGSTLSGHTDHSEPNKSAPLFSFSFGQTAIFLIGGRSLEEKPTAIYLQSGDVMIMSGESRLCYHAVPRIIKTQASATLSLIIEDVDNADIKTRTIDKDLFHDVGNPQFWEPFSRYMDDSRININIRQVLNPGDVKL.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	E. coli (Escherichia coli ), Fruit fly (Drosophila melanogaster)
Clone	MO0078YC
Specificity	This antibody binds to Escherichia coli K-12 alkB.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine. Accepts double-stranded and single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron. Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents).
Product Overview	Mouse Anti-E. coli alkB Antibody is a mouse antibody against alkB. It can be used for alkB detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative Names	Alpha-ketoglutarate-dependent dioxygenase AlkB; EC 1.14.11.33; Alkylated DNA repair protein AlkB; DNA oxidative demethylase AlkB; alkB; aidD; b2212 JW2200
UniProt ID	P05050
Protein Refseq	The length of the protein is 216 amino acids long. The sequence is show below: MLDLFADAEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGKKE.

For Research Use Only | Not For Clinical Use.

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