BCL2 Associated Athanogene 3
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
Mouse Anti-BAG3 Antibody (CBMOAB-25039FYC) (CAT#: CBMOAB-25039FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rhesus (Macaca mulatta), Pig (Sus scrofa), Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: BAG family molecular chaperone regulator 3
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: BCL2 Associated Athanogene 3, Bcl-2-Binding Protein Bis, Docking Protein CAIR-1, BAG-3, BIS, BAG Family Molecular Chaperone Regulator 3
Mouse Anti-BAG3 Antibody (MO-AB-51717W) (CAT#: MO-AB-51717W)
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- Host species: Mouse
- Species Reactivity: Marmoset, Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rhesus (Macaca mulatta), Pig (Sus scrofa), Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: BAG family molecular chaperone regulator 3
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: BAG family molecular chaperone regulator 3, BAG3
For Research Use Only | Not For Clinical Use.