Deoxyuridine 5'-triphosphate nucleotidohydrolase

This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.

  • Mouse Anti-Rice DUT Antibody (CBMOAB-22552FYB) (CAT#: CBMOAB-22552FYB)

    • Host species: Mouse
    • Species Reactivity: Rice (Oryza)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, EC 3.6.1.23, dUTP pyrophosphatase, DUT, Os03g0669100 LOC_Os03g46640

  • Mouse Anti-Arabidopsis DUT Antibody (CBMOAB-27933FYC) (CAT#: CBMOAB-27933FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Deoxyuridine Triphosphatase, DUTP Pyrophosphatase, DUTP Diphosphatase, EC 3.6.1.23, DUTPase, Deoxyuridine 5-Triphosphate Nucleotidohydrolase, Mitochondrial, DUTP Nucleotidohydrolase

  • Mouse Anti-Rhesus DUT Antibody (MO-AB-01959W) (CAT#: MO-AB-01959W)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 1, DUT

  • Mouse Anti-Cattle DUT Antibody (MO-AB-11751R) (CAT#: MO-AB-11751R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Deoxyuridine triphosphatase, DUT

  • Mouse Anti-Chimpanzee DUT Antibody (MO-AB-25528W) (CAT#: MO-AB-25528W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Deoxyuridine triphosphatase, DUT

  • Mouse Anti-Marmoset DUT Antibody (MO-AB-54601W) (CAT#: MO-AB-54601W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform 1, DUT

  • Mouse Anti-E. coli dut Antibody (CBMOAB-0629YC) (CAT#: CBMOAB-0629YC)

    • Host species: Mouse
    • Species Reactivity: E. coli (Escherichia coli )
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, EC 3.6.1.23, dUTP pyrophosphatase, dut, dnaS sof, b3640 JW3615

  • Mouse Anti-Zebrafish dut Antibody (CBMOAB-74250FYA) (CAT#: CBMOAB-74250FYA)

    • Host species: Mouse
    • Species Reactivity: Zebrafish (Danio rerio)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: DUTP pyrophosphatase, Dut protein, du

  • Mouse Anti-Frog dut Antibody (MO-AB-03132H) (CAT#: MO-AB-03132H)

    • Host species: Mouse
    • Species Reactivity: Frog (Xenopus laevis)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: LOC100037200 protein, dut, LOC100037200

  • Mouse Anti-Rat Dut Antibody (MO-AB-25515H) (CAT#: MO-AB-25515H)

    • Host species: Mouse
    • Species Reactivity: Rat (Rattus norvegicus)
    • Application: WB, ELISA
    • Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, EC 3.6.1.23, PPAR-interacting protein 4, PIP4, dUTP pyrophosphatase, Dut, Dutp
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