Fructose-1,6-bisphosphatase 1
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Mouse Anti-Fbp1 Antibody (CBMOAB-16588FYA) (CAT#: CBMOAB-16588FYA)
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- Host species: Mouse
- Species Reactivity: Fruit fly (Drosophila melanogaster), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chicken (Gallus gallus), French-bean, Frog (Xenopus laevis), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Sheep (Ovis aries), Yeast
- Application: WB, ELISA
- Protein: Fat-body protein 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Fat-body protein 1, P1 protein, Fbp1, P1
Mouse Anti-FBP1 Antibody (MO-AB-55286W) (CAT#: MO-AB-55286W)
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- Host species: Mouse
- Species Reactivity: Marmoset, C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chicken (Gallus gallus), French-bean, Frog (Xenopus laevis), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Sheep (Ovis aries), Yeast
- Application: WB, ELISA
- Protein: Fructose-bisphosphatase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Fructose-1,6-bisphosphatase 1, FBP1
For Research Use Only | Not For Clinical Use.
