Gen homolog 1, endonuclease
This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.
Mouse Anti-C. elegans GEN1 Antibody (CBMOAB-04378HCB) (CAT#: CBMOAB-04378HCB)
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- Host species: Mouse
- Species Reactivity: C. elegans (Caenorhabditis elegans)
- Application: WB, ELISA
- Protein: Submitted name: GEN1 Holliday junction resolvase homolog
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Protein GEN-1, gen-1
Mouse Anti-Arabidopsis GEN1 Antibody (CBMOAB-33945FYC) (CAT#: CBMOAB-33945FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: WB, ELISA
- Protein: Flap endonuclease GEN-like 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: GEN1, Holliday Junction 5' Flap Endonuclease, GEN1, Holliday Junction 5 Flap Endonuclease, Holliday Junction Resolvase, Gen Endonuclease Homolog 1 (Drosophila), Flap Endonuclease GEN Homolog 1, Gen Endonuclease Homolog 1, EC 3.1.-.-, Gen
Mouse Anti-Rhesus GEN1 Antibody (CBMOAB-43520FYA) (CAT#: CBMOAB-43520FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: GEN1 Holliday junction 5' flap endonuclease
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: GEN1
Mouse Anti-Chimpanzee GEN1 Antibody (MO-AB-18525W) (CAT#: MO-AB-18525W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: Submitted name: GEN1 Holliday junction 5' flap endonuclease
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Gen homolog 1, endonuclease, GEN1
