Mouse Anti-C. elegans GEN1 Antibody (CBMOAB-04378HCB)
Cat: CBMOAB-04378HCB
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | MO04378HB |
| Specificity | This antibody binds to C. elegans GEN1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. |
| Product Overview | Mouse Anti-C. elegans GEN1 Antibody is a mouse antibody against GEN1. It can be used for GEN1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Protein GEN-1; gen-1 |
| UniProt ID | Q22418 |
| Protein Refseq | The length of the protein is 434 amino acids long. The sequence is show below: MTINGIWEWANHVVRKVPNETMRDKTLSIDGHIWLYESLKGCEAHHQQTPNSYLVTFFTRIQRLLELKIIPIVVFDNINASSSAHESKDQNEFVPRKRRSFGDSPFTNLVDHVYKTNALLTELGIKVIIAPGDGEAQCARLEDLGVTSGCITTDFDYFLFGGKNLYRFDFTAGTSSTACLHDIMHLSLGRMFMEKKVSRPHLISTAILLGCDYFQRGVQNIGIVSVFDILGEFGDDGNEEIDPHVILDRFASYVREEIPARSEDTQRKLRLRRKKYNFPVGFPNCDAVHNAITMYLRPPVSSEIPKIIPRAANFQQVAEIMMKECGWPATRTQKELALSIRRKVHLTTTVAQTRIPDFFAATKSKNFTPIVEPCESLEDYISANNTWMRKRKRSESPQILQHHAKRQVPDRKRSVKIRAFKPYPTDVIELGDSD. |
See other products for " GEN1 "
| MO-AB-18525W | Mouse Anti-Chimpanzee GEN1 Antibody (MO-AB-18525W) |
| CBMOAB-33945FYC | Mouse Anti-Arabidopsis GEN1 Antibody (CBMOAB-33945FYC) |
| CBMOAB-43520FYA | Mouse Anti-Rhesus GEN1 Antibody (CBMOAB-43520FYA) |
For Research Use Only | Not For Clinical Use.
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