Poly(ADP ribose) polymerase 1
Participates in the base excision repair (BER) pathway by catalyzing the poly(ADP-ribosylation) of a limited number of receptor proteins involved in chromatin structure and DNA metabolism. This modification follows DNA damage and occurs as a mandatory step in the detection/signaling pathway, leading to the repair of DNA strand breaks (PubMed:17177976, PubMed:18172500, PubMed:19344625, PubMed:19661379, PubMed:23230272). Mediates poly(ADP-ribosylation) of APLF and CHFR (PubMed:17396150). Positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. Together with EEF1A1 and TXK, form a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-γ to directly regulate its transcription, thus playing an important role in Th1 cytokine production (PubMed: 17177976). Recruitment of PARP9 and DTX3L to DNA damage sites is required (PubMed:23230272). PARP1-dependent PARP9-DTX3L-mediated ubiquitination promotes rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80 and BRCA1 to sites of DNA damage (PubMed:23230272). Mediates serine ADP ribosylation of target proteins after interaction with HPF1; HPF1 confers serine specificity (PubMed:28190768). Mediates histone multimerization (ADP-ribosylation) in an HPF1-dependent manner (PubMed:27067600). Involved in ATP synthesis in the nucleus along with NMNAT1, PARG and NUDT5 (PubMed:27257257). Nuclear ATP production is required for energy-intensive chromatin remodeling events (PubMed:27257257).
Mouse Anti-Arabidopsis PARP1 Antibody (CBMOAB-38137FYC) (CAT#: CBMOAB-38137FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: Poly(ADP-Ribose) Polymerase 1, ADP-Ribosyltransferase (NAD+, Poly (ADP-Ribose) Polymerase), ADP-Ribosyltransferase Diphtheria Toxin-Like 1, Poly (ADP-Ribose) Polymerase Family, Member 1, NAD(+) ADP-Ribosyltransferase 1, Poly[ADP-Ribose] Synthase 1, EC 2.4.2.30, ADPRT 1, PARP-1, ADPRT, ARTD1
Mouse Anti-Rice PARP1 Antibody (CBMOAB-88473FYB) (CAT#: CBMOAB-88473FYB)
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- Host species: Mouse
- Species Reactivity: Rice (Oryza)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Poly [ADP-ribose] polymerase 1, PARP-1, EC 2.4.2.30, NAD(+) ADP-ribosyltransferase 1, ADPRT-1, Poly[ADP-ribose] synthase 1, PARP1, Os07g0413700 LOC_Os07g23110
Mouse Anti-Chicken PARP1 Antibody (MO-AB-03331Y) (CAT#: MO-AB-03331Y)
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- Host species: Mouse
- Species Reactivity: Chicken (Gallus gallus)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Poly [ADP-ribose] polymerase 1, PARP1
Mouse Anti-Chimpanzee PARP1 Antibody (MO-AB-11857W) (CAT#: MO-AB-11857W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Poly (ADP-ribose) polymerase 1, PARP1
Mouse Anti-Cattle PARP1 Antibody (MO-AB-17564R) (CAT#: MO-AB-17564R)
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- Host species: Mouse
- Species Reactivity: Cattle (Bos taurus)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Poly [ADP-ribose] polymerase 1, PARP-1, EC 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, PARP1, ADPRT
Mouse Anti-Hamsters PARP1 Antibody (MO-AB-43341W) (CAT#: MO-AB-43341W)
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- Host species: Mouse
- Species Reactivity: Hamsters (Cricetinae)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Poly [ADP-ribose] polymerase 1, PARP-1, EC 2.4.2.30, ADP-ribosyltransferase diphtheria toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, PARP1, ADPRT
Mouse Anti-Marmoset PARP1 Antibody (MO-AB-61017W) (CAT#: MO-AB-61017W)
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- Host species: Mouse
- Species Reactivity: Marmoset
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Poly [ADP-ribose] polymerase 1, PARP1
Mouse Anti-PARP1 Antibody (MOF032922W121) (CAT#: MOF032922W121)
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- Host species: Mouse
- Species Reactivity: Human, Chicken
- Application: WB
- Protein: Poly(ADP ribose) polymerase 1
- Size: 100µL
- Conjugate: NONE
- Alternative Names: PARP-1, Poly(ADP ribose) polymerase 1, sPARP1, ADPRT1, ADP ribosyltransferase NAD(+)
Mouse Anti-Zebrafish parp1 Antibody (CBMOAB-91452FYA) (CAT#: CBMOAB-91452FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: parp1, Poly(ADP-Ribose) Polymerase 1
Mouse Anti-Frog parp1 Antibody (MO-AB-06020H) (CAT#: MO-AB-06020H)
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- Host species: Mouse
- Species Reactivity: Frog (Xenopus laevis)
- Application: WB, ELISA
- Protein: Poly [ADP-ribose] polymerase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: PARP protein, parp1, PARP
Mouse Anti-Sheep Parp1 Antibody (MO-AB-17027Y) (CAT#: MO-AB-17027Y)
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- Host species: Mouse
- Species Reactivity: Sheep (Ovis aries)
- Application: WB, ELISA
- Protein: Submitted name: Poly(ADP-ribose) synthetase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Poly(ADP-ribose) synthetase, Parp1
