Rabbit Anti-ACO1 Antibody (MO-DKB-0020RA)

Cat: MO-DKB-0020RA
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Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana); S. lycopersicum (Solanum lycopersicum)
SpecificityThis antibody binds to Arabidopsis thaliana ACO1.
ImmunogenArabidopsis ACO1
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified serum

Application Information

Application NotesWestern Blot: 1:5000-1:10000


IntroductionAconitase is a single subunit enzyme of the tricarboxylic acid cycle (or Krebs cycle) in the mitochondria. A cytosolic isoform is also part of the glyoxylate cycle. Aconitase catalyzes the dehydration / hydration of citrate to iso-citrate, via cis-aconitate as an intermediate. The reaction is facilitated by an iron-sulphur cluster in the active site of the enzyme. The iron-sulphur cluster is somewhat unstable, especially under oxidative stress, and loss of the cofactor leads to degradation of the protein.
Alternative NamesACO; citrate hydro-lyase 1;2;3
UniProt IDQ42560
For Research Use Only | Not For Clinical Use.
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