Rabbit Anti-AGO1 (C-terminal) Antibody (Cat MO-DKB-03977W)


Cat: MO-DKB-03977W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
SpecificityThis antibody is binds to A. thaliana AGO1.
ImmunogenA GST-fusion protein containing the C-terminal region of arabidopsis thaliana AGO1 (At1g48410).
EpitopeC-terminal
FormatLiquid or Lyophilized
BufferPBS, pH 7.4, 100 ug/mL BSA, 40% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified

Application Information

ApplicationWB
Application NotesWestern Blot: 1:1000-1:3000
The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
Product OverviewThis product is a Rabbit antibody against the AGO1. It can be used for AGO1 detection in Western Blot.
Alternative NamesArgonaute 1, RISC Catalytic Component; Argonaute RISC Catalytic Component 1; Eukaryotic Translation Initiation Factor 2C, 1; Putative RNA-Binding Protein Q99; Argonaute1; EIF-2C 1; EIF2C 1; EIF2C1; HAgo1; Protein argonaute 1; ATAGO1; ICU9; ARGONAUTE 1
UniProt IDO04379
For Research Use Only | Not For Clinical Use.
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