Mouse Anti-AHR Antibody (MO-AB-07123Y)


Cat: MO-AB-07123Y
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-07123Y Monoclonal Rabbit (Oryctolagus cuniculus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), E. coli (Escherichia coli ), Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Marmoset, Pig (Sus scrofa) WB, ELISA MO07123Y 100 µg
CBMOAB-0067YC Monoclonal E. coli (Escherichia coli ) WB, ELISA MO0067YC 100 µg
MO-AB-21150W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO21150W 100 µg
MO-AB-41201W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO41201W 100 µg
MO-AB-50616W Monoclonal Marmoset WB, ELISA MO50616W 100 µg
MO-AB-23646R Monoclonal Pig (Sus scrofa) WB, ELISA MO23646R 100 µg
MO-AB-01304H Monoclonal Frog (Xenopus laevis) WB, ELISA MO01304C 100 µg
MO-AB-00091Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO00091Y 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRabbit (Oryctolagus cuniculus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), E. coli (Escherichia coli ), Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Marmoset, Pig (Sus scrofa)
CloneMO07123Y
SpecificityThis antibody binds to Rabbit AHR.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Nucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionLigand-activated transcriptional activator (PubMed:9022676). Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. The heterodimer ARNT:AHR binds to core DNA sequence 5''-TGCGTG-3'' within the dioxin response element (DRE) of target gene promoters and activates their transcription (By similarity).
Product OverviewThis product is a mouse antibody against AHR. It can be used for AHR detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesAryl hydrocarbon receptor; AHR
UniProt IDG1SKL6
Protein RefseqThe length of the protein is 862 amino acids long. The sequence is show below: MRTLWSHLSPRWQILAVDLTKMAPGGRRDGLRHHAPGVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSSSADRNGGQDPCRAKFGEGLNLQEGEFLLQALNGFVLVVTVDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDPGQGADETHGLPQPVYYNPDQLPPENSSFMERCFICRLRCLLDNSSGFLAMNFQGRLKFLHGQNKKGKDGSLLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPTGCDAKGQIVLGYTEAELCMRGSGYQFIHAADMLYCAESHIRMIKTGESGLAVFRLLTKDNRWAWVQSNARFIYKNGRPDFIIATQRPLTDEEGREHLLKRNTKLPFMFTTGEAVLYEMTSPFPPIMDPLPIRPKSGTCGKDSATKPTPSKDSVHPSSLLSALMQQDESIYLYPPSSNAPFERNFFTESLNECSNWPENVASVAGGSVLKHEQIGQSQEVSPAFSGDQTVLFPDNKNCDLYNIMKNLGVDFEDIKNMQNEEFFGADFSGEVDFRDIDITDEILTYVQDSLNKSPFGSPGYQPQPATALNSSCMVQERLQLGPPQQPPCRSEQATVEPQQQLCQKMEHMQVNSMFANWSANQPVPFSEPQQDLQPYSVFTDFHTADQAFPYTAAMNTMPYTQNFTPCNQTVAPQHSRCTQLDFAMGNFDSSPYPSTSNLEDFVTCLQVPDRQTHGGNPQSAMVAPQTCYAGAVSMYQCQPGPAHTLMGQMQCEPPVPGPEAFLNKFPNGGMLNETYPADLHDINNTVASTHLPPLHHPSEARPFPDLASGRLL.
For Research Use Only | Not For Clinical Use.
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