Rabbit Anti-AK2 Antibody (MO-DKB-01188W)


Cat: MO-DKB-01188W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Rat (Rattus norvegicus), Mouse (Mus musculus), Bovine (Bos taurus), Rhesus (Macaca mulatta)
ImmunogenA recombinant protein containing the sequence of the central region of human adenylate kinase 2.
EpitopeThe epitope is in the Center of AK2.
FormatLiquid or Lyophilized
Buffer0.1M Tris, pH 7, 0.1M Glycine, 10% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified
Cellular LocalizationMitochondrion intermembrane space

Application Information

ApplicationWB, IF, IHC, IHC-P
Application NotesWestern Blot 1:500-1:3000
Immunocytochemistry/Immunofluorescence 1:100-1:1000
Immunohistochemistry 1:100-1:1000
Immunohistochemistry-Paraffin 1:100-1:1000

Target

IntroductionAdenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq, Nov 2010]
Product OverviewThis product is a Rabbit antibody against the Center of the AK2. It can be used for AK2 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesAdenylate Kinase 2; Adenylate Monophosphate Kinase; ATP-AMP Transphosphorylase 2; ATP:AMP Phosphotransferase; EC 2.7.4.3; ADK2;
Gene ID204
UniProt IDP54819
For Research Use Only | Not For Clinical Use.
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