Rabbit Anti-BMP4 Antibody (MOFY-0722-FY387)


Cat: MOFY-0722-FY387
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Specifications

Host speciesRabbit
Species ReactivityGoat
FormatLiquid or Lyophilized
BufferPBS, pH7.4, 50% glycerol
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A

Application Information

ApplicationWB, IHC, ICC, IP
Application NotesWB: 0.5-2 µg/mL
IHC: 5-20 µg/mL
ICC: 5-20 µg/mL
The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]
Alternative NamesBone Morphogenetic Protein 4; Bone Morphogenetic Protein 2B; BMP2B; BMP2B1; MCOPS6; BMP-2B;
For Research Use Only | Not For Clinical Use.
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