Rabbit Anti-BMP4 Antibody (MO-DKB-00288W)


Cat: MO-DKB-00288W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human BMP4 and has cross reactivity with Mouse, Zebrafish.
ImmunogenRecombinant human bone morphogenetic protein 4 protein
EpitopeThe epitope is in the AA 303-408 of BMP4.
FormatLiquid or Lyophilized
BufferPBS pH 7.4, 50% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 95% was determined by SDS-PAEG
PurificationPurified with G affinity chromatography

Application Information

ApplicationELISA, WB, IHC
Application NotesWestern Blot: 1:500-1:5000
Immunohistochemistry: 1:100-1:1000

Target

IntroductionThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Product OverviewThis product is a rabbit antibody against the AA 303-408 of the BMP4. It can be used for BMP4 detection in Enzyme-Linked Immunosorbent Assay, Western Blot, Immunohistochemistry.
Alternative NamesBone morphogenetic protein 4 preproprotein; BMP4
UniProt IDP12644
For Research Use Only | Not For Clinical Use.
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