Mouse Anti-Cattle NPRL2 Antibody (MO-AB-16892R)
Cat: MO-AB-16892R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO16892R |
Specificity | This antibody binds to Cattle NPRL2. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Lysosome; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. |
Product Overview | This product is a mouse antibody against NPRL2. It can be used for NPRL2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Nitrogen permease regulator 2-like protein; NPR2-like protein; Tumor suppressor candidate 4; NPRL2; TUSC4 |
UniProt ID | Q5E9U9 |
Protein Refseq | The length of the protein is 380 amino acids long. The sequence is show below: MGSSCRIECIFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSTEESKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQRPDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLV. |
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For Research Use Only | Not For Clinical Use.
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