Mouse Anti-D. melanogaster Nprl2 Antibody (CBMOAB-25910FYA)
Cat: CBMOAB-25910FYA
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO25910FYA |
| Specificity | This antibody binds to fruit fly Nprl2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations; Lysosome |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. |
| Product Overview | Mouse Anti-D. melanogaster Nprl2 Antibody is a mouse antibody against Nprl2. It can be used for Nprl2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | CG9104-PA; LD40282p; Nprl2 |
| UniProt ID | Q9VXA0 |
| Protein Refseq | The length of the protein is 412 amino acids long. The sequence is show below: MHSHTNETAATSTTAGAVTNGAGGSGAGAAGAHGSTEGKIRCIFLSEFHATAGCKISCQVPDNYISKDVFDAINVYIIPKQHLQRCILTVNAMDVKIVGYPVGIQDQQKYARNAFLFNLCFVCDSRARSVQYEPVVKKLSEYLIMMEEESCFLSREDDKRRLQNIFETVLRDLNERKVATIVEGDNTIYLKIVMHKPDPPPVKDHMVPLLLANLRDAPLDNWDLTTQQILPYINGINHVARIAAEADVETDLVKSCIQNLVYYGVVQLLPILKYSNVYMTQNLKHLIQSASLSGACRKYVALRPDKTLPSVQRIFQFYASMTHGVTLRAICQRLCPQHHNIDERRMVIFGLQHRFIRCIHKYPVFTGSVPSGRQKMYTGLISFDEICCKTGLSPCTIERDIEKDTNVTVIWK. |
See other products for " NPRL2 "
| MO-AB-16892R | Mouse Anti-Cattle NPRL2 Antibody (MO-AB-16892R) |
| MO-AB-05737H | Mouse Anti-Frog nprl2 Antibody (MO-AB-05737H) |
| MO-AB-18335W | Mouse Anti-Chimpanzee NPRL2 Antibody (MO-AB-18335W) |
| CBMOAB-52918FYA | Mouse Anti-Rhesus NPRL2 Antibody (CBMOAB-52918FYA) |
| MO-AB-60273W | Mouse Anti-Marmoset NPRL2 Antibody (MO-AB-60273W) |
| CBMOAB-89778FYA | Mouse Anti-Zebrafish nprl2 Antibody (CBMOAB-89778FYA) |
| CBMOAB-07744HCB | Mouse Anti-C. elegans NPRL2 Antibody (CBMOAB-07744HCB) |
For Research Use Only | Not For Clinical Use.
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