Mouse Anti-Rhesus NPRL2 Antibody (CBMOAB-52918FYA)


Cat: CBMOAB-52918FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO52918FYA
SpecificityThis antibody binds to Rhesus NPRL2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionAs a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
Product OverviewMouse Anti-Rhesus NPRL2 Antibody is a mouse antibody against NPRL2. It can be used for NPRL2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesNPRL2
UniProt IDF7F5X2
Protein RefseqThe length of the protein is 380 amino acids long.
The sequence is show below: MGSGCRIECIFFSEFHPTLGPKITYQVPEDFISRELFDTVQVYIITKPELQNKLITVTAMEKKLIGCPVCIEHKKYSRNALLFNLGFVCDAQAKTCALEPIVKKLAGYLTTLELESSFVSTEESKQKLVPIMTILLEELNASGRCTLPIDESNTIHLKVIEQRPDPPVAQEYDVPVFTKDKEDFFNSQWDLTTQQILPYIDGFRHVQKISAEADVELNLVRIAIQNLLYYGVVTLVSILQYSNVYCPTPKVQDLVDDKSLQEACLSYVTKQGHKRASLRDVFQLYCSLSPGITVRDLIGRHPQQLQHVDERKLIQFGLMKNLIRRLQKYPVRVSREEQSHPARLYTGCHSYDEICCKTGMSYHELDERLENDPNIIICWK.
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For Research Use Only | Not For Clinical Use.
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