Mouse Anti-Cattle SDHB Antibody (MO-AB-19859R)
Cat: MO-AB-19859R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO19859R |
Specificity | This antibody binds to Cattle SDHB. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Mitochondrion |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. |
Product Overview | This product is a mouse antibody against SDHB. It can be used for SDHB detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; EC 1.3.5.1; Iron-sulfur subunit of complex II; IP; SDHB |
UniProt ID | Q3T189 |
Protein Refseq | The length of the protein is 280 amino acids long. The sequence is show below: MAAVVALSLRRRFPAAALGGARLQACRGAQTAAAAAPRIKKFAIYRWDPDKTGDKPHMQTYEIDLNNCGPMVLDALIKIKNEIDSTLTFRRSCREGICGSCAMNINGGNTLACTRRIDTNLSKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPYLKKKDESQGGKEQYLQSIEDREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAVLMQAYRWMIDSRDDFTEERLAKLQDPFSLYRCHTIMNCTQTCPK. |
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For Research Use Only | Not For Clinical Use.
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