Mouse Anti-CD4 Antibody (MO-AB-07529Y)


Cat: MO-AB-07529Y
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
  • Reference
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MO-AB-07529Y Monoclonal Rabbit (Oryctolagus cuniculus), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chicken, Turkey, Quail, Pigeon, Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Feline, Lion, Goat (Capra hircus), Sheep (Ovis aries), Horse (Equus caballus), Human (Homo sapiens), Fruit fly (Drosophila melanogaster), Primate, Rhesus (Macaca mulatta), Mallard (Anas platyrhynchos), Medaka (Oryzias latipes), Mouse (Mus musculus), Pig (Sus scrofa), Porcine, Rhesus, Human, Mouse WB, ELISA MO07529Y 100 µg
CBMOAB-00057FYA Monoclonal Cattle (Bos taurus) FC F00057FYA 100 µg
CBMOAB-00058FYA Monoclonal Cattle (Bos taurus) FC F00058FYA 100 µg
CBMOAB-00059FYA Monoclonal Cattle (Bos taurus) FC F00059FYA 100 µg
CBMOAB-00060FYA Monoclonal Cattle (Bos taurus) FC F00060FYA 100 µg
CBMOAB-00138FYA Monoclonal Dog (Canis lupus familiaris) FC F00138FYA 100 µg
CBMOAB-00142FYA Monoclonal Goat (Capra hircus), Sheep (Ovis aries) FC F00142FYA 100 µg
CBMOAB-00149FYA Monoclonal Horse (Equus caballus) FC F00149FYA 100 µg
CBMOAB-00150FYA Monoclonal Horse (Equus caballus) FC F00150FYA 100 µg
CBMOAB-00156FYA Monoclonal Cat (Felis catus) FC F00156FYA 100 µg
CBMOAB-00181FYA Monoclonal Rabbit (Oryctolagus cuniculus) FC F00181FYA 100 µg
MO-NAB-00173W Monoclonal Human (Homo sapiens), Primate, Rhesus (Macaca mulatta) WB, FC, IHC, IHC-P, IP, CyTOF-ready, IF MT310 100 µg
MO-AB-21077W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO21077W 100 µg
MO-AB-29467W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO29467W 100 µg
MO-AB-36875W Monoclonal Goat (Capra hircus) WB, ELISA MO36875W 100 µg
MO-AB-09834R Monoclonal Cattle (Bos taurus) WB, ELISA MO09834R 100 µg
MO-AB-00183R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO00183R 100 µg
MO-AB-24462R Monoclonal Pig (Sus scrofa) WB, ELISA MO24462R 100 µg
MO-AB-23021H Monoclonal Mallard (Anas platyrhynchos) WB, ELISA MO23021C 100 µg
MO-AB-01062Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO01062Y 100 µg
MO-NAB-00315W Monoclonal Mouse (Mus musculus) ELISA, FC NW0243 100 µg
MO-DKB-00481W Polyclonal Human (Homo sapiens), Fruit fly (Drosophila melanogaster) WB, IHC, IHC-P, IHC-WhMt 100 µg
MOFY-0522-FY2 Monoclonal Chicken, Turkey, Quail, Pigeon FC, IHC, IP, BL 100 µg
MOFY-0522-FY27 Monoclonal Chicken, Turkey FC, IP 100 µg
MOFY-0522-FY52 Monoclonal Porcine FC 100 µg
MOFY-0522-FY71 Monoclonal Feline, Lion FC, IHC 100 µg
MOFY-0722-FY429 Polyclonal Rhesus, Human, Mouse WB, IHC, ICC, IP 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRabbit (Oryctolagus cuniculus), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chicken, Turkey, Quail, Pigeon, Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Feline, Lion, Goat (Capra hircus), Sheep (Ovis aries), Horse (Equus caballus), Human (Homo sapiens), Fruit fly (Drosophila melanogaster), Primate, Rhesus (Macaca mulatta), Mallard (Anas platyrhynchos), Medaka (Oryzias latipes), Mouse (Mus musculus), Pig (Sus scrofa), Porcine, Rhesus, Human, Mouse
CloneMO07529Y
SpecificityThis antibody binds to Rabbit CD4.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionIntegral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
Product OverviewThis product is a mouse antibody against CD4. It can be used for CD4 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesT-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD antigen CD4; CD4
UniProt IDP46630
Protein RefseqThe length of the protein is 459 amino acids long. The sequence is show below: MNRRIYFQCLLLVLPLALLPAATWGKTVVRGKAGAIVELPCQSSQKRNSVFNWKHANQVKILGNQGSSSSSFWLKGNSPLSNRVESKKNMWDQGSFPLVIKDLRMDDSGTYICEVGDKKMEVELLVFRLTANPNTRLLHGQSLTLTLEGPSVGSPSVQWKSPENKIIETGPTCSMPKLRLQDSGTWSCHLSFQDQNKLELDIKIIVLGFPKASATVYKKEGEQVEFSFPLNFEDESLSGELMWQVDGASSAQSWVSFSLEDRKVSVQKILPDLKIQMSKGLPLSLTLPQALHRYAGSGNLSLTLDKGKLHQQVSLVMLKVTQVKNKLTCEVLGPIDPKMKLSLKLEDQEAKVSTQKMVQVLDPKAGTWQCLLSSGDQVLLESKADVLATGLSHQQPTLLAGALGGTAGLVLFAGLCIYCCVKCRHRRHQAQRMSQIKKLLSEKKTCQCPHRLQKTYNLL.

Reference

Reference1. Kotani, M., Yamamura, Y., Tamatani, T., Kitamura, F., & Miyasaka, M. (1993). Generation and characterization of monoclomal antibodies against rabbit CD4, CD5 and CD11a antigens. Journal of immunological methods, 157(1-2), 241-252.
2. Sawasdikosol, S., Hague, B. F., Zhao, T. M., Bowers, F. S., Simpson, R. M., Robinson, M., & Kindt, T. J. (1993). Selection of rabbit CD4-CD8-T cell receptor-gamma/delta cells by in vitro transformation with human T lymphotropic virus-I. The Journal of experimental medicine, 178(4), 1337-1345.
For Research Use Only | Not For Clinical Use.
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