Mouse Anti-Chicken ARNT Antibody (MO-AB-00174Y)


Cat: MO-AB-00174Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityChicken (Gallus gallus)
CloneMO00174Y
SpecificityThis antibody binds to Chicken ARNT.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionRequired for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer binds to core DNA sequence 5''-TACGTG-3'' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5''-TGCGTG-3'' within the dioxin response element (DRE) of target gene promoters and activates their transcription (By similarity).
Product OverviewThis product is a mouse antibody against ARNT. It can be used for ARNT detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesAryl hydrocarbon receptor nuclear translocator; ARNT
UniProt IDQ98SN3
Protein RefseqThe length of the protein is 805 amino acids long. The sequence is show below: MAATAANPEMASDVSSLGAAVGSGNPGAGAQTGGGIVQRAAKRRPGLDFDDDGEGNSKFLRCDDDPMPNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGTYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVGKLREQLSTSENALTEGTKPWCLSNKDPAAPPESASKGRILDLKTGTVKKEGQQSMRMCMGSRRSFICRMRCGNSSVDAVSVNRLSFMRNRCRNGLGATKDGEPHYVVVHCTGYIKAWPPAGVSLPDDDPDAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQPTEFISRHNTEGIFTFIDHRCVATVGYQPQELLGKDIVDFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKNREWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQDSRPALSNPMQRPQLGQSVSLPLEMGTAQLPSRQQQQPQQTELEVVPGRESLAGYDHAQVPVQPVSAAGPEHSKPLEKAESLFNQERDPRFGEIYGSINADQNKAIPASSVPANPTLFPQGNAFTPSRPAENFRSSSMVPPVNIIQQQPAAAGRILAQISRHASPAQVSGSSWAAGTRPAFAAQVASQAVKTRPPSFSMGTFQGTPASFSPMAAPGSTASPSSAAYPNLSGRSAGFTTDAAQTPTPFQPRAAAEGVGMWPQWQGQHHSTAAGEQHVQQPSQPEAFPDMLTMLGDQGPNYNNEEFPELNIFPSFSE.
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For Research Use Only | Not For Clinical Use.
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