Mouse Anti-Frog arnt Antibody (MO-AB-01599H)


Cat: MO-AB-01599H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO01599C
SpecificityThis antibody binds to Frog arnt.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.
Product OverviewThis product is a mouse antibody against arnt. It can be used for arnt detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesArnt.2 protein; arnt; arnt.2
UniProt IDQ6P6Z6
Protein RefseqThe length of the protein is 765 amino acids long.
The sequence is show below: MASDVPALGVAVSTGNPGSSAQAGGSMVQRANKRRSGLDFDDDDDDDTGNKFLRCDDDDDQLPNDKERFARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMKSLRGTGNTPTDGTYKPSFLTDQELKHLILEAADGFLFVVSCETGRIVYVSDSVTPVLNQHQSEWFGSSVYDQVHPDDLDKLREQLSTAENAMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAVIESSSMNRLSFMRNRCRNGLGPSKDGEPQFVVVHCTGYIKAWPPAGVTLPDDDPDAGQSSKFCLVAIGRLQVTSSPTCTDMNTVCQPIEFISRHSVDGLFTFVDHRCTATVGYQPQELLGKDIVEFAHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRSKTREWLLMRTSSFTFQNPYSDEIEYIICTNTNVKNSNQEPRPALASTIQRPPLAPSINHPMDMGPTQLPGRQQQPQAPPQADVVSNREGLGSYNHTQVPVQPIGSAVPDHSKPLEKTESIYGQDRDPRFVEIYSNINSDQNKSINPSVVSGNQQLFQQSGTFTSAPRPVETFRSGGMVPQPSIIQQPVSTGQMLAQISRHTSPTQVTGTNWSSGTRPSFTAQQVPTQTPKTQASQFGTGNFQATPSNFSHLSSQSSASTPAGASYSSMNSRTNNFAAEVAQPRGQFQTRAGDSVGVWPPWQSQHHGHSTAESHVSQQSNQTEVFPDMLSMLGDQTSSYNNEEFSELNMFQSFAE.
For Research Use Only | Not For Clinical Use.
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