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- Mouse Anti-D. melanogaster MYC (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL), clone 9E10) Antibody (MO-NAB-00006W)
Mouse Anti-D. melanogaster MYC (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL), clone 9E10) Antibody (MO-NAB-00006W)
Cat: MO-NAB-00006W
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Fruit fly (Drosophila melanogaster) |
Clone | 9E10 |
Specificity | Specific for the c-myc protein in random coil configuration, not as a helix. 9E10 does not react with V-myc. |
Immunogen | A synthetic peptide corresponding to the amino acid (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) of the human c-Myc antibody (9E10). |
Epitope | AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL) |
Format | Liquid or Lyophilized |
Buffer | PBS |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Protein G purified |
Application Information
Application | WB, ChIP, ELISA, FC, FC-IC, IB, IF, IHC, IHC-Fr, IHC-P, IP |
Application Notes | WB: 0.5-2.0 ug/ml WB: 1/200 ELISA: 1/100-1/2000 FC: 1/50-1/200 IF: 1/50-1/200 IHC: 1/50-1/200 IHC-Fr: 1/50-1/200 IHC-P: 1/50-1/200 IP: 1/10-1/500 |
Target
Introduction | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] |
Product Overview | Mouse Anti-D. melanogaster MYC (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL), clone 9E10) Antibody (MO-NAB-00006W) is a Mouse antibody against the epitope (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL)) of thec-Myc. It can be used for c-Myc detection in Western Blot, Chromatin Immunoprecipitation, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Flow Cytometry-IC,Immunoblotting, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation. |
Alternative Names | MYC Proto-Oncogene, BHLH Transcription Factor; V-Myc Avian Myelocytomatosis Viral Oncogene Homolog; Class E Basic Helix-Loop-Helix Protein 39; Transcription Factor P64; Proto-Oncogene C-Myc; BHLHe39; Myc-Related Translation/Localization Regulatory Factor |
Gene ID | 4609 |
UniProt ID | P01106 |
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For Research Use Only | Not For Clinical Use.
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