Mouse Anti-D. melanogaster MYC (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL), clone 9E10) Antibody (MO-NAB-00006W)


Cat: MO-NAB-00006W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Fruit fly (Drosophila melanogaster)
Clone9E10
SpecificitySpecific for the c-myc protein in random coil configuration, not as a helix. 9E10 does not react with V-myc.
ImmunogenA synthetic peptide corresponding to the amino acid (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) of the human c-Myc antibody (9E10).
EpitopeAA 408-439, Leucine zipper sequence (AEEQKLISEEDLL)
FormatLiquid or Lyophilized
BufferPBS
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein G purified

Application Information

ApplicationWB, ChIP, ELISA, FC, FC-IC, IB, IF, IHC, IHC-Fr, IHC-P, IP
Application NotesWB: 0.5-2.0 ug/ml
WB: 1/200
ELISA: 1/100-1/2000
FC: 1/50-1/200
IF: 1/50-1/200
IHC: 1/50-1/200
IHC-Fr: 1/50-1/200
IHC-P: 1/50-1/200
IP: 1/10-1/500

Target

IntroductionThis gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Product OverviewMouse Anti-D. melanogaster MYC (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL), clone 9E10) Antibody (MO-NAB-00006W) is a Mouse antibody against the epitope (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL)) of thec-Myc. It can be used for c-Myc detection in Western Blot, Chromatin Immunoprecipitation, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Flow Cytometry-IC,Immunoblotting, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation.
Alternative NamesMYC Proto-Oncogene, BHLH Transcription Factor; V-Myc Avian Myelocytomatosis Viral Oncogene Homolog; Class E Basic Helix-Loop-Helix Protein 39; Transcription Factor P64; Proto-Oncogene C-Myc; BHLHe39; Myc-Related Translation/Localization Regulatory Factor
Gene ID4609
UniProt IDP01106
For Research Use Only | Not For Clinical Use.
Online Inquiry