Mouse Anti-Dog MYC Antibody (MO-AB-31855W)
Cat: MO-AB-31855W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Dog (Canis lupus familiaris) |
| Clone | MO31855W |
| Specificity | This antibody binds to Dog MYC. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. |
| Product Overview | Mouse Anti-Dog MYC Antibody is a mouse antibody against MYC. It can be used for MYC detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Myc proto-oncogene protein; Proto-oncogene c-Myc; Transcription factor p64; MYC |
| UniProt ID | Q28350 |
| Protein Refseq | The length of the protein is 439 amino acids long. The sequence is show below: MPLNVSFANRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVASFSPRGDDDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPSPARGPGGCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKPCASPDSAAFSPSSDSLLSSAESSPRASPEPLALHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPAKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRARLDSGRVLKQISNNRKCASPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLLSEKDLLRKRREQLKHKLEQLRNSGA. |
See other products for " MYC "
| MO-AB-16231Y | Mouse Anti-Sheep MYC Antibody (MO-AB-16231Y) |
| MOFY-0522-FY164 | Mouse Anti-Myc Antibody (MOFY-0522-FY164) |
| MO-AB-35156W | Mouse Anti-Ferret MYC Antibody (MO-AB-35156W) |
| MO-DKB-00580W | Rabbit Anti-MYC Antibody (MO-DKB-00580W) |
| MO-NAB-00006W | Mouse Anti-D. melanogaster MYC (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL), clone 9E10) Antibody (MO-NAB-00006W) |
| MO-AB-09453W | Mouse Anti-Cat MYC Antibody (MO-AB-09453W) |
| MO-NAB-00831W | Mouse Anti-Drosophila Myc Antibody |
| MO-NAB-00248W | Rabbit Anti-Yeast MYC Antibody (MO-NAB-00248W) |
| CBMOAB-52008FYA | Mouse Anti-Rhesus MYC Antibody (CBMOAB-52008FYA) |
| MO-AB-27436R | Mouse Anti-Pig MYC Antibody (MO-AB-27436R) |
For Research Use Only | Not For Clinical Use.
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