Rabbit Anti-MYC Antibody (MO-DKB-00580W)
Cat: MO-DKB-00580W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Insect, Yeast |
| Immunogen | Synthetic peptide against human c-Myc antibody [Uniprot: P01106] |
| Epitope | The epitope is in the AA 385-435 of MYC. |
| Format | Liquid or Lyophilized |
| Buffer | Tris-Glycine, 0.15 M NaCl |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Affinity purified |
| Cellular Localization | Cytoplasmic and Nuclear |
Application Information
| Application | WB, Simple Western, ChIP, ELISA, IF, IHC, IHC-P, IP |
| Application Notes | Western Blot 1:1000 Simple Western 1:500 Chromatin Immunoprecipitation ELISA 1:1000 Immunocytochemistry/Immunofluorescence 1:50 Immunohistochemistry 1:100 Immunohistochemistry-Paraffin 1:100 Immunoprecipitation 1:1000 |
Target
| Introduction | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] |
| Product Overview | This product is a Rabbit antibody against the AA 385-435 of the MYC. It can be used for MYC detection in Western Blot, Simple Western, Chromatin Immunoprecipitation, Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation. |
| Alternative Names | MYC Proto-Oncogene, BHLH Transcription Factor; V-Myc Avian Myelocytomatosis Viral Oncogene Homolog; Class E Basic Helix-Loop-Helix Protein 39; Transcription Factor P64; Proto-Oncogene C-Myc; BHLHe39; Myc-Related Translation/Localization Regulatory Factor; |
| Gene ID | 4609 |
| UniProt ID | P01106 |
See other products for " MYC "
| MO-AB-16273R | Mouse Anti-Cattle MYC Antibody (MO-AB-16273R) |
| MO-AB-10125W | Mouse Anti-Chimpanzee MYC Antibody (MO-AB-10125W) |
| MO-AB-09453W | Mouse Anti-Cat MYC Antibody (MO-AB-09453W) |
| MO-AB-31855W | Mouse Anti-Dog MYC Antibody (MO-AB-31855W) |
| MO-AB-12129Y | Mouse Anti-O. mykiss myc Antibody (MO-AB-12129Y) |
| MO-AB-23485H | Mouse Anti-Mallard MYC Antibody (MO-AB-23485H) |
| MO-NAB-00248W | Rabbit Anti-Yeast MYC Antibody (MO-NAB-00248W) |
| CBMOAB-52008FYA | Mouse Anti-Rhesus MYC Antibody (CBMOAB-52008FYA) |
| MO-NAB-00006W | Mouse Anti-D. melanogaster MYC (AA 408-439, Leucine zipper sequence (AEEQKLISEEDLL), clone 9E10) Antibody (MO-NAB-00006W) |
| MO-AB-27436R | Mouse Anti-Pig MYC Antibody (MO-AB-27436R) |
For Research Use Only | Not For Clinical Use.
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