Mouse Anti-Drosophila Myc Antibody


Cat: MO-NAB-00831W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityD. melanogaster (Drosophila melanogaster)
CloneNW0753
SpecificityThis antibody is binds to D. melanogaster Myc.
FormatLiquid or Lyophilized
BufferSupernatant
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationChIP, IF, IHC, IP, WB

Target

IntroductionParticipates in the regulation of gene transcription (PubMed:8929412, PubMed:16087886, PubMed:24173801, PubMed:24615015, PubMed:25999153, PubMed:25858587). Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence CAC[GA]TG (PubMed:8929412). Seems to activate the transcription of growth-related genes; required for cellular proliferation and growth (PubMed:16087886, PubMed:25999153, PubMed:25858587). Functions in the TORC2-mediated regulation of cell growth, acting downstream of the TORC2 complex (PubMed:25999153). Inhibits the demethylase activity of Lid (PubMed:17311883). Activates transcription of mbm (PubMed:24615015). Has a role in ribosome biogenesis and endoreplication in fat body cells by activating the transcription of LTV1 (PubMed:25858587). Able to induce the SCF E3 ubiquitin-protein ligase member archipelago (ago) which functions in its degradation (PubMed:15182669, PubMed:24173801). It may therefore create a negative feedback loop with ago that is regulated by the ubiquitin hydrolase puf (PubMed:24173801).
Product OverviewThis product is a Mouse antibody against the epitope of the Myc. It can be used for Myc detection in Chromatin Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot.
Alternative NamesMyc protein; Diminutive protein; dMyc1; dMyc; dm
Gene ID31310
UniProt IDQ9W4S7
For Research Use Only | Not For Clinical Use.
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