Mouse Anti-D. melanogaster Sdhb Antibody (CBMOAB-30667FYA)


Cat: CBMOAB-30667FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO30667FYA
SpecificityThis antibody binds to fruit fly Sdhb.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationMitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComplex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Product OverviewMouse Anti-D. melanogaster Sdhb Antibody is a mouse antibody against Sdhb. It can be used for Sdhb detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; EC 1.3.5.1; Iron-sulfur subunit of complex II; Ip; SdhB; SDH
UniProt IDP21914
Protein RefseqThe length of the protein is 297 amino acids long.
The sequence is show below: MLATEARQILSRVGSLVARNQMRAISNGTAQLEQQAQPKEAQEPQIKKFEIYRWNPDNAGEKPYMQTYEVDLRECGPMVLDALIKIKNEMDPTLTFRRSCREGICGSCAMNIGGTNTLACISKIDINTSKSLKVYPLPHMYVVRDLVPDMNNFYEQYRNIQPWLQRKNEAGEKKGKAQYLQSVEDRSKLDGLYECILCACCSTSCPSYWWNAEKYLGPAVLMQAYRWIIDSRDENSAERLNKLKDPFSVYRCHTIMNCTRTCPKGLNPGRAIAEIKKLLSGLASKPAPKLETAALHK.
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For Research Use Only | Not For Clinical Use.
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