Mouse Anti-Dog Tg Antibody (MO-AB-33701W)
Cat: MO-AB-33701W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Dog (Canis lupus familiaris) |
| Clone | MO33701W |
| Specificity | This antibody binds to Dog Tg. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. |
| Product Overview | Mouse Anti-Dog Tg Antibody is a mouse antibody against Tg. It can be used for Tg detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Thyroglobulin; Tg |
| UniProt ID | Q1ERT3 |
| Protein Refseq | The length of the protein is 2762 amino acids long. The sequence is show below: MALALWVFSLLGSACVVSANIFEYQVDAQPLRPCELQRERAFLKGAEYVPQCAEDGSYQTVQCQNDGRTCWCVGADGVEVPGSRQPARPAACLSFCQLQRQQILLSGYLNSTATSYLPQCQESGGYAPVQCDLWQQQCWCVDAEGMEVYGTRQLGRPARCPRSCDIRNRRLLHGVGDKSPPQCSPDGAFMPVQCKFVNTTDMMIFDLVHSYNRFPDAFVTFSAFRSKFPDVSGYCHCADSLGRELAGTGLELLLDEIYDTIFAGLDLASTFAETTLYRILQRRFLAVQLVLSGRFRCPTRCEVEQFTASSFGHPYTPSCRRDGGFQAVQCQRGGPCWCVDARGKEIPGTRRPGERPSCAETQLCASERRQALSRLFFGPSGYFSQHSLFLAPDGRQVSQRVARFATSCPPLIKELFVDSGILRPMVEGQDKQFSASETLIREAIGAIFPSRELARLALQFTTDPTRLQQNLFGGKFLVNVGRFNLSGAIGTRGTFNFSQFFQQFGLPGFQNSETDLAQPLSVGLDSQPATAPPEASKEGTAMNVPVVGSFGFQINLQENQNALTFLASLLELPEFLLFLQHAISVPEDIAKDLGDVMEMVLSSQDCEQTPGNLFVPQCSAEGDYEDVQCFAGECWCVDSRGKELAGSRVRGGRPRCPTECEKQRALMRSLSGSLPAGASLFVPSCTSEGHFLPVQRFNSECYCVDTNGQAIPGTRSLPGEPKQCPTPCQLQAEQAFLGIVQVLGSDSSMLPTFSSSYIPQCSTAGQWRPVQCDGPPEQAFEWHERWEAQNNSGQELTPAELLMKIMSYREAASGSFRLFIQSLYAAGQQGIFPGLARYPSFEDVPLAVMEGNRTQPGGNILLEPYLFWQILNGQLSRYPGAYSDFSAPLAHFDLRSCWCVSEAGRELEGTRTEPSKVPACPGSCEEVKLRVLQFLKETEEIVLASNSSWFPLGESFLAAKGIWLTDEELSLPRLSPSRETFSEKFLSGGDYALRLAAQSTLDFYQRRGFLLGDSTRTSALLRPVPYVPQCDVWGGWEPVQCHARTGYCWCVDGKGEYVPASLTARSPRILRCPTACEKSRASGLLSSWKQAGSQGNPSPKDLFIPTCLETGEFARRQESEGGTWCVDPGSGAGRPPGTDSSAPCPSLCEELSSGTLSRRASSGYSPACRAEDGGFSPVQCDLAQGSCWCVLDSGEEVPGTRVAGSQLACESPRCPLPFNTTDVDGGVIVCERASGPGGAPVQRCQLLCRRGYRSAFLPGPLVCSLEEGRWLSQPPQPQACQRPHLWQTFQTQGQFQLQLPPGKMCSADYAGLLPAFQVFLADELEARGFCQIQAKTLGTPISIPVCDSSTVQVECVTGERLGVNVTWKLHLEDVPPASLPDLHDIEEALVGKDLIGRFTDLIQSGGFQLHLDSKTFPADTSIYFLQGDRFGTSPRAWFGCLEGFHQVLAPSNAPQDPWGCVKCPEGSYFQKEICIPCPVGFYQEQAGSMDCVPCPVGRTTISPGAFSHTHCVTDCQRSEVGLRCDQDGQYRASQRDGAGGKAFCVDGEGRRLPWSETEAPLTDSQCQMMQKFEKAPDSKVVFSANVTAVGRSKVSGSGSPLLQCLTDCALDETCSFLAVSTAGSEVSCDFYGWTSDSIACTTSAQHQDTLGNSEATSFGSLRCQMTVRSGAQDSLAVYLKKGQEFTTTSQKSFEQTGFQNMLSGLYRPVIFPASGADLTAAHLFCLLACDRDSCCDGFILAQLQGGPVICGLLSSPDVLLCHVKDWRDPTEAQANATCPGVTYDRGSRQATLRLGGQEFRVPVALEGTSGTVTSFQRVYLWKESDMGSRSESMGCRRDMEPRPASPTETDLTTELFSPVDLDQVIVNGSQSLPSQQHWLFKHLFSPQQANLWCLSRCVQEPSFCQLVEITDSAPLYFTCALYPEARVCDSVMESSPKGCRLILPHRPETLFRKKVILRDKVKNFYTRLPFQKLMGISIRNKMPMSEKSISNGFFECERLCDADPCCTGFGFLNVSQLTGGEVTCLTLNSLGLQTCSEENMGAWRILDCGSPDTEVRTYPFGWYQKPAARNDAPSFCPVVTPPSLPEKVTLGSWQSLAPSAVVIDSSIRNFDVAHVSTATTNDFSDARDFCLLECSRHQACLVTTLRAQPGAVRCVFYADAQICTHSLQAQNCQLLLREEATHIYRKLNIPLLSFGTSVPSVTITPHGQLLGRSQAIQVGTSWKQVDQFLGVPYATPPLAESRFRAPEPLNWTGSWDATKPRASCWQPGTRTLESPGVDEDCLYLNVFVPQNVAPNASVLVFFHNTLEGRGSEGPLAIDGSYLAAIGNLIVVTAGYRVGIFGFLSSGSGELSGNWGLLDQLAALTWVQTHIGVFGGDPRRVTLAADRGGADVASIHLLTTRAADSRLFRRAILMGGSAFSPAVVISQGRAQEQAAALAEEIGCPTSSTQELVSCLRQKPASILNDAQTKLLAVSGPFHYWGPVVDGQYLREAPARALQRTLRAKVDLLIGSSQDDGLINRAKAVKQFEESQGRTSSKTAFYQALQNSLGGEDADAGVRAAATWYYSLEHSTDDYASFSRALENATRDYFITCPVIDMASHWARRARGNVFMYHAPESYDHRSLELLADVQYAFGLPFYPVYEGQFTLEEKSLSLKIMQFFSNFVRSGNPNYPHEFSRKASELAAPWPDFVPRTGGESYKEFSVLLPNRQGLKSADCSFWAKYIQSLKAVADEAKQELSAESEEDDEPADSGLIGEPGSKSYSK. |
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For Research Use Only | Not For Clinical Use.
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