Mouse Anti-Drosophila Fmr1 Antibody (RGG region)


Cat: MO-NAB-00704W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityD. melanogaster (Drosophila melanogaster)
CloneNW0626
SpecificityThis antibody is binds to D. melanogaster Fmr1.
ImmunogenRecombinant GST-dFmr1 protein with N-terminal 600 aa.
EpitopeThe epitope is in the RGG region of Fmr1
FormatLiquid or Lyophilized
BufferSupernatant
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationIF, IHC, IP, WB

Target

IntroductionThe protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Product OverviewThis product is a Mouse antibody against the RGG region of the Fmr1. It can be used for Fmr1 detection in Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot.
Alternative NamesFragile X mental retardation syndrome-related protein 1; dFMR1; dfxr; Fmr1; FXR
Gene ID37528
UniProt IDQ9NFU0
For Research Use Only | Not For Clinical Use.
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