Mouse Anti-D. melanogaster FMR1 (C-terminal, clone 6A15) Antibody (MO-NAB-00048W)
Cat: MO-NAB-00048W
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Fruit fly (Drosophila melanogaster) |
Clone | 6A15 |
Immunogen | His-dFMR1 fusion protein (Drosophila) (C-terminal 580aa). |
Epitope | C-terminal |
Format | Liquid or Lyophilized |
Buffer | PBS |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Protein A Purified |
Cellular Localization | Cytoplasmic |
Application Information
Application | IP, IF, ELISA, WB |
Application Notes | IP: 25 µg/mg |
Target
Introduction | The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010] |
Product Overview | Mouse Anti-D. melanogaster FMR1 (C-terminal, clone 6A15) Antibody (MO-NAB-00048W) is a Mouse antibody against the epitope (C-terminal) of theFMR1. It can be used for FMR1 detection in Immunoprecipitation, Immunofluorescence, Enzyme-Linked Immunosorbent Assay, Western Blot. |
Alternative Names | Fragile X Mental Retardation 1; Fragile X Mental Retardation Protein 1; FMRP; Synaptic Functional Regulator FMR1; Premature Ovarian Failure 1; Protein FMR-1; FRAXA; POF1; POF |
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For Research Use Only | Not For Clinical Use.
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