Mouse Anti-D. melanogaster FMR1 (C-terminal, clone 6A15) Antibody (MO-NAB-00048W)


Cat: MO-NAB-00048W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
Clone6A15
ImmunogenHis-dFMR1 fusion protein (Drosophila) (C-terminal 580aa).
EpitopeC-terminal
FormatLiquid or Lyophilized
BufferPBS
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A Purified
Cellular LocalizationCytoplasmic

Application Information

ApplicationIP, IF, ELISA, WB
Application NotesIP: 25 µg/mg

Target

IntroductionThe protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
Product OverviewMouse Anti-D. melanogaster FMR1 (C-terminal, clone 6A15) Antibody (MO-NAB-00048W) is a Mouse antibody against the epitope (C-terminal) of theFMR1. It can be used for FMR1 detection in Immunoprecipitation, Immunofluorescence, Enzyme-Linked Immunosorbent Assay, Western Blot.
Alternative NamesFragile X Mental Retardation 1; Fragile X Mental Retardation Protein 1; FMRP; Synaptic Functional Regulator FMR1; Premature Ovarian Failure 1; Protein FMR-1; FRAXA; POF1; POF
For Research Use Only | Not For Clinical Use.
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