Rabbit Anti-FMR1 Antibody (Cat MO-DKB-03649W)


Cat: MO-DKB-03649W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human FMRP and has cross reactivity with Mouse, Rat, Zebrafish FMRP.
ImmunogenKLH conjugated synthetic phosphopeptide, derived from human FMRP around the phosphorylation site of Ser500
FormatLiquid or Lyophilized
Buffer1% BSA, 50% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A purified
Cellular LocalizationCytoplasm, Nucleus

Application Information

ApplicationWB, ELISA, IHC-P, IHC-Fr, IF, ICC
Application NotesWestern Blot: 1:300-1000
Enzyme-Linked Immunosorbent Assay: 1:500-1000
Immunohistochemistry-Paraffin 1:200-400
Immunohistochemistry-Frozen: 1:100-500
Immunofluorescence:(Immunohistochemistry-Paraffin) 1:50-200
Immunofluorescence:(Immunohistochemistry-F) 1:50-200
Immunofluorescence/Immunocytochemistry: 1:50-200
Immunocytochemistry 1:100-500
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Product OverviewThis product is a Rabbit antibody against the FMRP. It can be used for FMRP detection in Western Blot, Enzyme-Linked Immunosorbent Assay, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunofluorescence, Immunocytochemistry.
Alternative NamesPOF; FMRP; POF1; FRAXA; Fragile X mental retardation protein 1; Protein FMR-1; FMR1
UniProt IDE7EYA6
For Research Use Only | Not For Clinical Use.
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