Rabbit Anti-FMR1 Antibody (Cat MO-DKB-03457W)
Cat: MO-DKB-03457W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens), Mouse (Mus musculus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Chicken (Gallus gallus), Primate, Sheep (Ovis aries), Frog (Xenopus), Zebrafish (Danio rerio) |
| Specificity | This antibody is specific to the ~71k FMRP protein phosphorylated at Ser499. Lambda-phosphatase completely eliminates the immunolabeling of FMRP protein. |
| Immunogen | The synthetic phosphopeptide corresponds to the amino acid residues around Ser499 conjugated to KLH. Registration number # Q80WE1 |
| Format | Liquid or Lyophilized |
| Buffer | 10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA, 50% Glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Affinity purified |
Application Information
| Application | WB |
| Application Notes | Western Blot: 1:1000 The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
| Product Overview | This product is a Rabbit antibody against the FMRP [p Ser499]. It can be used for FMRP [p Ser499] detection in Western Blot. |
| Alternative Names | fmr1; Fragile X Mental Retardation 1 |
| UniProt ID | E7EYA6 |
See other products for " FMR1 "
| MO-AB-25884R | Mouse Anti-Pig FMR1 Antibody (MO-AB-25884R) |
| MO-AB-25859H | Mouse Anti-Rat Fmr1 Antibody (MO-AB-25859H) |
| MOFY-0922-FY91 | Mouse Anti-FMR1 Antibody, IgG1 (MOFY-0922-FY91) |
| MO-NAB-00048W | Mouse Anti-D. melanogaster FMR1 (C-terminal, clone 6A15) Antibody (MO-NAB-00048W) |
| MO-NAB-00704W | Mouse Anti-Drosophila Fmr1 Antibody (RGG region) |
| MO-AB-12651R | Mouse Anti-Cattle FMR1 Antibody (MO-AB-12651R) |
| CBMOAB-76701FYA | Mouse Anti-Zebrafish fmr1 Antibody (CBMOAB-76701FYA) |
| MO-AB-55568W | Mouse Anti-Marmoset FMR1 Antibody (MO-AB-55568W) |
| MO-NAB-00703W | Mouse Anti-Drosophila Fmr1 Antibody (Full length) |
| MO-AB-15881W | Mouse Anti-Chimpanzee FMR1 Antibody (MO-AB-15881W) |
For Research Use Only | Not For Clinical Use.
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